Does exercise reduce brain oxidative stress? A systematic review

D. Camiletti-Moirón, V. A. Aparicio, P. Aranda, Zsolt Radak

Research output: Contribution to journalReview article

41 Citations (Scopus)

Abstract

The aim of the present systematic review was to investigate the influence of different exercise programs on brain oxidative stress. A search of the literature was conducted up to 1 December 2012 across five databases: PUBMED, SCOPUS, SPORTS DISCUS, Web of Science, and The Cochrane Library. The search strategy used in the electronic databases mentioned was established as: (swim* OR exercise OR training) AND ("oxidative stress" AND brain) for each database. A methodological quality assessment valuation/estimation was additionally carried out in the final sample of studies. Of 1553 potentially eligible papers, 19 were included after inclusion and exclusion criteria. The methodological quality assessment showed a total score in the Quality Index between 40% and 80%, with a mean quality of 56.8%. Overall, regular moderate aerobic exercise appears to promote antioxidant capacity on brain. In contrast, anaerobic or high-intensity exercise, aerobic-exhausted exercise, or the combination of both types of training could deteriorate the antioxidant response. Future investigations should be focused on establishing a standardized exercise protocol, depending on the exercise metabolism wanted to test, which could enhance the objective knowledge in this topic.

Original languageEnglish
JournalScandinavian Journal of Medicine and Science in Sports
Volume23
Issue number4
DOIs
Publication statusPublished - 2013 Aug 1
Externally publishedYes

Fingerprint

Oxidative Stress
Databases
Exercise
Brain
Antioxidants
PubMed
Libraries
Sports

Keywords

  • Aerobic exercise
  • Anaerobic exercise
  • Brain
  • Enzymatic activity
  • Exercise protocol
  • Oxidative stress
  • Physical extenuation
  • Rats

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Does exercise reduce brain oxidative stress? A systematic review. / Camiletti-Moirón, D.; Aparicio, V. A.; Aranda, P.; Radak, Zsolt.

In: Scandinavian Journal of Medicine and Science in Sports, Vol. 23, No. 4, 01.08.2013.

Research output: Contribution to journalReview article

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