"Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors

M. Hayashi, M. Chernov, N. Tamura, M. Tamura, M. Izawa, Y. Muragaki, H. Iseki, Y. Okada

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    Background Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases. Method and Results: Donuts shape radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met. Conclusion: Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed donuts shape dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.

    Original languageEnglish
    Pages (from-to)286-289
    Number of pages4
    JournalMinimally Invasive Neurosurgery
    Volume54
    Issue number5-6
    DOIs
    Publication statusPublished - 2011 Dec 1

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    Keywords

    • automatic positioning system
    • cystic neoplasms
    • gamma knife radiosurgery
    • intracranial metastasis
    • outcome
    • treatment

    ASJC Scopus subject areas

    • Surgery
    • Clinical Neurology

    Cite this

    Hayashi, M., Chernov, M., Tamura, N., Tamura, M., Izawa, M., Muragaki, Y., Iseki, H., & Okada, Y. (2011). "Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors. Minimally Invasive Neurosurgery, 54(5-6), 286-289. https://doi.org/10.1055/s-0031-1297987