Abstract
Background Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases. Method and Results: Donuts shape radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met. Conclusion: Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed donuts shape dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.
| Original language | English |
|---|---|
| Pages (from-to) | 286-289 |
| Number of pages | 4 |
| Journal | Minimally Invasive Neurosurgery |
| Volume | 54 |
| Issue number | 5-6 |
| DOIs | |
| Publication status | Published - 2011 |
| Externally published | Yes |
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Keywords
- automatic positioning system
- cystic neoplasms
- gamma knife radiosurgery
- intracranial metastasis
- outcome
- treatment
ASJC Scopus subject areas
- Clinical Neurology
- Surgery
Cite this
"Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors. / Hayashi, M.; Chernov, M.; Tamura, N.; Tamura, M.; Izawa, M.; Muragaki, Y.; Iseki, Hiroshi; Okada, Y.
In: Minimally Invasive Neurosurgery, Vol. 54, No. 5-6, 2011, p. 286-289.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - "Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors
AU - Hayashi, M.
AU - Chernov, M.
AU - Tamura, N.
AU - Tamura, M.
AU - Izawa, M.
AU - Muragaki, Y.
AU - Iseki, Hiroshi
AU - Okada, Y.
PY - 2011
Y1 - 2011
N2 - Background Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases. Method and Results: Donuts shape radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met. Conclusion: Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed donuts shape dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.
AB - Background Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases. Method and Results: Donuts shape radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met. Conclusion: Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed donuts shape dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.
KW - automatic positioning system
KW - cystic neoplasms
KW - gamma knife radiosurgery
KW - intracranial metastasis
KW - outcome
KW - treatment
UR - http://www.scopus.com/inward/record.url?scp=84856238289&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84856238289&partnerID=8YFLogxK
U2 - 10.1055/s-0031-1297987
DO - 10.1055/s-0031-1297987
M3 - Article
C2 - 22278800
AN - SCOPUS:84856238289
VL - 54
SP - 286
EP - 289
JO - Minimally Invasive Neurosurgery
JF - Minimally Invasive Neurosurgery
SN - 0946-7211
IS - 5-6
ER -