"Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors

M. Hayashi, M. Chernov, N. Tamura, M. Tamura, M. Izawa, Y. Muragaki, Hiroshi Iseki, Y. Okada

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases. Method and Results: Donuts shape radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met. Conclusion: Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed donuts shape dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.

Original languageEnglish
Pages (from-to)286-289
Number of pages4
JournalMinimally Invasive Neurosurgery
Volume54
Issue number5-6
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint

Radiosurgery
Brain Neoplasms
Capsules
Neoplasms
Neoplasm Metastasis
Therapeutics

Keywords

  • automatic positioning system
  • cystic neoplasms
  • gamma knife radiosurgery
  • intracranial metastasis
  • outcome
  • treatment

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Hayashi, M., Chernov, M., Tamura, N., Tamura, M., Izawa, M., Muragaki, Y., ... Okada, Y. (2011). "Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors. Minimally Invasive Neurosurgery, 54(5-6), 286-289. https://doi.org/10.1055/s-0031-1297987

"Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors. / Hayashi, M.; Chernov, M.; Tamura, N.; Tamura, M.; Izawa, M.; Muragaki, Y.; Iseki, Hiroshi; Okada, Y.

In: Minimally Invasive Neurosurgery, Vol. 54, No. 5-6, 2011, p. 286-289.

Research output: Contribution to journalArticle

Hayashi, M, Chernov, M, Tamura, N, Tamura, M, Izawa, M, Muragaki, Y, Iseki, H & Okada, Y 2011, '"Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors', Minimally Invasive Neurosurgery, vol. 54, no. 5-6, pp. 286-289. https://doi.org/10.1055/s-0031-1297987
Hayashi, M. ; Chernov, M. ; Tamura, N. ; Tamura, M. ; Izawa, M. ; Muragaki, Y. ; Iseki, Hiroshi ; Okada, Y. / "Donut's shape" radiosurgical treatment planning for large cystic metastatic brain tumors. In: Minimally Invasive Neurosurgery. 2011 ; Vol. 54, No. 5-6. pp. 286-289.
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