Dynamic cell patterning technology based on photocleavable molecules

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Dynamic control of cell-substrate interactions is useful for exploring signaling processes involved in cell adhesion and migration as well as patterning heterotypic cells to mimic living tissues. We have developed photoactivatable substrates whose surface was modified with photoreleasable cell-repellent blocking agents. The surfaces are initially non-cell adhesive because of the presence of the blocking agents, but become cell adhesive upon near-UV irradiation of the substrates via the photo-induced desorption of the blocking agents. Here, I overview the developmental process of our photoactivatable substrates and demonstrate their potential uses for bioanalysis.

Original languageEnglish
Title of host publicationEmerging Focus on Advanced Materials
Pages7-10
Number of pages4
DOIs
Publication statusPublished - 2011 Sep 27
Externally publishedYes
Event1st International Congress on Advanced Materials 2011, AM2011 - Jinan, China
Duration: 2011 May 132011 May 16

Publication series

NameAdvanced Materials Research
Volume306-307
ISSN (Print)1022-6680

Conference

Conference1st International Congress on Advanced Materials 2011, AM2011
CountryChina
CityJinan
Period11/5/1311/5/16

Keywords

  • Array
  • Caged compounds
  • Cell adhesion
  • Cloning
  • Migration

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Jun, N. (2011). Dynamic cell patterning technology based on photocleavable molecules. In Emerging Focus on Advanced Materials (pp. 7-10). (Advanced Materials Research; Vol. 306-307). https://doi.org/10.4028/www.scientific.net/AMR.306-307.7