Dynamics of Z-form DNA

Ikuo Ashikawa, Kazuhiko Kinosita, Akira Ikegami

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The torsional and bending rigidities of Z-form DNA have been studied by nanosecond fluorescence anisotropy measurements of intercalated ethidium. The results suggested that Z-form DNA was considerably more flexible than B-form DNA. We have investigated the temperature dependence of the rigidity of B- and Z-form DNA and found that the temperature dependence of the torsional rigidity of Z-form DNA was remarkably lower than that of B-form DNA.

Original languageEnglish
Pages (from-to)87-93
Number of pages7
JournalBBA - Gene Structure and Expression
Volume782
Issue number1
DOIs
Publication statusPublished - 1984 May 15
Externally publishedYes

Fingerprint

Z-Form DNA
B-Form DNA
Rigidity
Temperature
Fluorescence Polarization
Ethidium
Anisotropy
Fluorescence

Keywords

  • DNA dynamics
  • Ethidium bromide
  • Fluorescence anisotropy
  • Helix rigidity
  • Z-DNA

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Genetics
  • Structural Biology

Cite this

Ashikawa, I., Kinosita, K., & Ikegami, A. (1984). Dynamics of Z-form DNA. BBA - Gene Structure and Expression, 782(1), 87-93. https://doi.org/10.1016/0167-4781(84)90109-X

Dynamics of Z-form DNA. / Ashikawa, Ikuo; Kinosita, Kazuhiko; Ikegami, Akira.

In: BBA - Gene Structure and Expression, Vol. 782, No. 1, 15.05.1984, p. 87-93.

Research output: Contribution to journalArticle

Ashikawa, I, Kinosita, K & Ikegami, A 1984, 'Dynamics of Z-form DNA', BBA - Gene Structure and Expression, vol. 782, no. 1, pp. 87-93. https://doi.org/10.1016/0167-4781(84)90109-X
Ashikawa, Ikuo ; Kinosita, Kazuhiko ; Ikegami, Akira. / Dynamics of Z-form DNA. In: BBA - Gene Structure and Expression. 1984 ; Vol. 782, No. 1. pp. 87-93.
@article{1678cdebf4534d85856b5d243dbe9c46,
title = "Dynamics of Z-form DNA",
abstract = "The torsional and bending rigidities of Z-form DNA have been studied by nanosecond fluorescence anisotropy measurements of intercalated ethidium. The results suggested that Z-form DNA was considerably more flexible than B-form DNA. We have investigated the temperature dependence of the rigidity of B- and Z-form DNA and found that the temperature dependence of the torsional rigidity of Z-form DNA was remarkably lower than that of B-form DNA.",
keywords = "DNA dynamics, Ethidium bromide, Fluorescence anisotropy, Helix rigidity, Z-DNA",
author = "Ikuo Ashikawa and Kazuhiko Kinosita and Akira Ikegami",
year = "1984",
month = "5",
day = "15",
doi = "10.1016/0167-4781(84)90109-X",
language = "English",
volume = "782",
pages = "87--93",
journal = "Biochimica et Biophysica Acta - Gene Structure and Expression",
issn = "0167-4781",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Dynamics of Z-form DNA

AU - Ashikawa, Ikuo

AU - Kinosita, Kazuhiko

AU - Ikegami, Akira

PY - 1984/5/15

Y1 - 1984/5/15

N2 - The torsional and bending rigidities of Z-form DNA have been studied by nanosecond fluorescence anisotropy measurements of intercalated ethidium. The results suggested that Z-form DNA was considerably more flexible than B-form DNA. We have investigated the temperature dependence of the rigidity of B- and Z-form DNA and found that the temperature dependence of the torsional rigidity of Z-form DNA was remarkably lower than that of B-form DNA.

AB - The torsional and bending rigidities of Z-form DNA have been studied by nanosecond fluorescence anisotropy measurements of intercalated ethidium. The results suggested that Z-form DNA was considerably more flexible than B-form DNA. We have investigated the temperature dependence of the rigidity of B- and Z-form DNA and found that the temperature dependence of the torsional rigidity of Z-form DNA was remarkably lower than that of B-form DNA.

KW - DNA dynamics

KW - Ethidium bromide

KW - Fluorescence anisotropy

KW - Helix rigidity

KW - Z-DNA

UR - http://www.scopus.com/inward/record.url?scp=0021361487&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021361487&partnerID=8YFLogxK

U2 - 10.1016/0167-4781(84)90109-X

DO - 10.1016/0167-4781(84)90109-X

M3 - Article

C2 - 6722160

AN - SCOPUS:0021361487

VL - 782

SP - 87

EP - 93

JO - Biochimica et Biophysica Acta - Gene Structure and Expression

JF - Biochimica et Biophysica Acta - Gene Structure and Expression

SN - 0167-4781

IS - 1

ER -