Effect of 2 days of intensive resistance training on appetite-related hormone and anabolic hormone responses

Kazushige Goto, Kohei Shioda, Sunao Uchida

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

This study was designed to determine endocrine responses during 2 days of strenuous resistance training. Ten healthy men performed resistance training twice a day for two successive days to induce acute fatigue (excessive physical stress). The resistance training consisted of four exercises for the lower body in the morning and seven exercises for the upper body in the afternoon. Maximal isometric and isokinetic strengths were measured from day 1 (before the training period) to day 3 (after the training period). Fasting blood samples were taken on days 1-3. Maximal isometric and isokinetic strengths significantly decreased with two successive days of training (P<0·05), with significant increases in serum creatine phosphokinase and myoglobin concentrations (P<0·05). Significant reductions in the fasting concentrations of serum insulin-like growth factor-1, free testosterone, insulin and high-molecular-weight adiponectin were observed on day 3 (P<0·05), whereas there were no changes in the serum cortisol concentration or the free testosterone/cortisol ratio. Plasma active ghrelin and serum leptin concentrations decreased by -20·7 ± 2·8% and -29·6 ± 4·1%, respectively (P<0·05). Two days strenuous resistance training significantly affects the profiles of anabolic hormone and endocrine regulators of appetite and energy balance, such as ghrelin and leptin. The present findings suggest that decreased ghrelin and leptin concentrations might reflect excessive physical stress and may be early signs of accumulated fatigue.

Original languageEnglish
Pages (from-to)131-136
Number of pages6
JournalClinical Physiology and Functional Imaging
Volume33
Issue number2
DOIs
Publication statusPublished - 2013 Mar
Externally publishedYes

Fingerprint

Resistance Training
Appetite
Ghrelin
Leptin
Hormones
Serum
Fatigue
Hydrocortisone
Fasting
Exercise
Myoglobin
Adiponectin
Somatomedins
Creatine Kinase
Testosterone
Molecular Weight
Insulin

Keywords

  • Appetite
  • Endocrine response
  • Energy balance
  • Fatigue
  • Increased training volume

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

Effect of 2 days of intensive resistance training on appetite-related hormone and anabolic hormone responses. / Goto, Kazushige; Shioda, Kohei; Uchida, Sunao.

In: Clinical Physiology and Functional Imaging, Vol. 33, No. 2, 03.2013, p. 131-136.

Research output: Contribution to journalArticle

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