Abstract
The addition of 2-deoxy-d-glucose and related glucose analogues to the cultures of Coprinus macrorhizus resulted in the induction of tyrosinase production and inhibition of fruiting body formation. The induction was inhibited by cycloheximide or high concentrations of glucose. Electrophoretic analyses revealed that tyrosinase, peroxidase, and tyrosinase inhibitors were present in crude mycelial extracts and that the production of an unusual tyrosinase isozyme was responsible for the enzyme induction.
| Original language | English |
|---|---|
| Pages (from-to) | 229-238 |
| Number of pages | 10 |
| Journal | The Journal of General and Applied Microbiology |
| Volume | 26 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1980 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Microbiology
- Applied Microbiology and Biotechnology
Cite this
Effect of 2-deoxy-d-glucose on the induction of tyrosinase in Coprinus macrorhizus. / Nyunoya, Hiroshi; Ishikawa, Tatsuno.
In: The Journal of General and Applied Microbiology, Vol. 26, No. 3, 1980, p. 229-238.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of 2-deoxy-d-glucose on the induction of tyrosinase in Coprinus macrorhizus
AU - Nyunoya, Hiroshi
AU - Ishikawa, Tatsuno
PY - 1980
Y1 - 1980
N2 - The addition of 2-deoxy-d-glucose and related glucose analogues to the cultures of Coprinus macrorhizus resulted in the induction of tyrosinase production and inhibition of fruiting body formation. The induction was inhibited by cycloheximide or high concentrations of glucose. Electrophoretic analyses revealed that tyrosinase, peroxidase, and tyrosinase inhibitors were present in crude mycelial extracts and that the production of an unusual tyrosinase isozyme was responsible for the enzyme induction.
AB - The addition of 2-deoxy-d-glucose and related glucose analogues to the cultures of Coprinus macrorhizus resulted in the induction of tyrosinase production and inhibition of fruiting body formation. The induction was inhibited by cycloheximide or high concentrations of glucose. Electrophoretic analyses revealed that tyrosinase, peroxidase, and tyrosinase inhibitors were present in crude mycelial extracts and that the production of an unusual tyrosinase isozyme was responsible for the enzyme induction.
UR - http://www.scopus.com/inward/record.url?scp=0019185020&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019185020&partnerID=8YFLogxK
U2 - 10.2323/jgam.26.229
DO - 10.2323/jgam.26.229
M3 - Article
VL - 26
SP - 229
EP - 238
JO - Journal of General and Applied Microbiology
JF - Journal of General and Applied Microbiology
SN - 0022-1260
IS - 3
ER -