Effect of 2-deoxy-d-glucose on the induction of tyrosinase in Coprinus macrorhizus

Hiroshi Nyunoya, Tatsuno Ishikawa

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


The addition of 2-deoxy-d-glucose and related glucose analogues to the cultures of Coprinus macrorhizus resulted in the induction of tyrosinase production and inhibition of fruiting body formation. The induction was inhibited by cycloheximide or high concentrations of glucose. Electrophoretic analyses revealed that tyrosinase, peroxidase, and tyrosinase inhibitors were present in crude mycelial extracts and that the production of an unusual tyrosinase isozyme was responsible for the enzyme induction.

Original languageEnglish
Pages (from-to)229-238
Number of pages10
JournalThe Journal of General and Applied Microbiology
Issue number3
Publication statusPublished - 1980 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology

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