Effect of a sports drink based on highly-branched cyclic dextrin on cytokine responses to exhaustive endurance exercise

Katsuhiko Suzuki, K. Shiraishi, K. Yoshitani, K. Sugama, T. Kometani

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    BACKGROUND: Aim of the present study was to compare the effects of highly branched cyclic dextrin (HBCD) drink with a glucose-based control drink on immunoendocrine responses to endurance exercise.

    METHODS: Using a randomized, double-blind placebo-controlled cross-over design, seven male triathletes participated in two duathlon races separated by one month, consisting of 5 km of running, 40 km of cycling and 5 km of running. In the first race, four athletes consumed the HBCD-based drink and three athletes consumed the glucose-based drink. In the second race, three athletes consumed the HBCD-based drink and four athletes consumed the glucose-based drink. We collected blood and urine samples before and after the races to analyze leukocyte count and concentrations of hormones and cytokines.

    RESULTS: Lymphocyte and neutrophil counts increased significantly after exercise in both trials (P<0.05), but were not significantly different between the trials. Plasma noradrenalin concentration increased significantly (P<0.05) during exercise in the glucose trial, but not in the HBCD trial. Plasma concentrations of interleukin (IL)-8 and IL-10 increased significantly during exercise in both trials (P<0.05) but were not significantly different between the trials. Post-race urinary IL-8, IL-10 and IL-12p40 concentrations were significantly lower in the HBCD trial compared with the glucose trial (P<0.05), although the plasma concentrations of these cytokines were not significantly different between both trials.

    CONCLUSION: These results suggest that the HBCD-based drink may attenuate the stress hormone response, and reduce the urinary cytokine levels following exhaustive exercise.

    Original languageEnglish
    Pages (from-to)622-630
    Number of pages9
    JournalThe Journal of sports medicine and physical fitness
    Volume54
    Issue number5
    Publication statusPublished - 2014 Oct 1

    Fingerprint

    Sports
    Exercise
    Cytokines
    Athletes
    Glucose
    Interleukin-8
    Running
    Interleukin-10
    Hormones
    Interleukins
    Lymphocyte Count
    Leukocyte Count
    Cross-Over Studies
    caloreen
    Norepinephrine
    Neutrophils
    Placebos
    Urine

    ASJC Scopus subject areas

    • Orthopedics and Sports Medicine
    • Physical Therapy, Sports Therapy and Rehabilitation

    Cite this

    Effect of a sports drink based on highly-branched cyclic dextrin on cytokine responses to exhaustive endurance exercise. / Suzuki, Katsuhiko; Shiraishi, K.; Yoshitani, K.; Sugama, K.; Kometani, T.

    In: The Journal of sports medicine and physical fitness, Vol. 54, No. 5, 01.10.2014, p. 622-630.

    Research output: Contribution to journalArticle

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