Effect of acute maximal exercise on circulating levels of interleukin-12 during Ramadan fasting

Salma Abedelmalek, Nizar Souissi, Takayuki Akimoto, Sami Hadouk, Zouhair Tabka

Research output: Contribution to journalArticle

8 Citations (Scopus)


Purpose: The purpose of this study was to examine the effects of Ramadan fasting on circulating levels of interleukin-12 (IL-12) after a brief maximal exercise. Methods: Nine subjects performed a Wingate test on three different occasions: (i) the first week of Ramadan (1WR), (ii) the fourth week of Ramadan (4WR), and (iii) three weeks after Ramadan (AR). Blood samples were taken before, immediately and 60 min after the exercise. Plasma concentrations of IL-12 were measured using enzyme-linked immunosorbent assay. Variance analysis revealed no significant effect of Ramadan on Ppeak and Pmean during the three testing periods. Results: Considering the effect of Ramadan on plasma concentrations of IL-12, analysis of the variance revealed a significant Ramadan effect (F(2, 16) = 66.27; P(2, 16)= 120.66; P(4, 32) = 2.40; P>0.05). For all measures, IL-12 levels were lower during 1WR and 4WR in comparison with AR (P

Original languageEnglish
Pages (from-to)154-160
Number of pages7
JournalAsian Journal of Sports Medicine
Issue number3 SPEC. ISSUE
Publication statusPublished - 2011
Externally publishedYes



  • Immunity
  • Interleukin-12
  • Ramadan
  • Sleep deprivation
  • Wingate test

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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