Effect of anisotropy on stress-induced electrical potentials in bovine bone using ultrasound irradiation

S. Matsukawa, T. Makino, S. Mori, D. Koyama, S. Takayanagi, K. Mizuno, Takahiko Yanagitani, M. Matsukawa

    Research output: Contribution to journalArticle

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    Abstract

    The bone fracture healing mechanism of the low-intensity pulsed ultrasound technique is not yet clearly understood. In our previous study, the electrical potentials induced in bone were successfully measured by focusing on piezoelectricity in the MHz range. Bone is composed of collagen and hydroxyapatite and has strong anisotropy. The purpose of this study is to investigate the effects of bone anisotropy on the electrical potentials induced by ultrasound irradiation. For this study, ultrasound bone transducers were fabricated using cortical bovine bone plates as piezoelectric devices. An ultrasound of 7.4 kPapeak-peak (i.e., the peak-to-peak pressure value) was used to irradiate the side surface of each bone plate. Electrical potentials induced in the bone plate were then measured by varying the wave propagation direction in the plate. The peak-to-peak values of these ultrasonically induced electrical potentials were found to vary with changes in the ultrasound propagation direction in the bone sample. The potential was maximized at an inclination of approximately 45° to the bone axis but was minimized around the three orthogonal directions. These maxima and minima ranged from 28 to 33 μVpeak-peak and from 5 to 12 μVpeak-peak, respectively. Additionally, our ultrasound results indicated a change in polarity due to bone anisotropy in the MHz range.

    Original languageEnglish
    Article number143701
    JournalApplied Physics Letters
    Volume110
    Issue number14
    DOIs
    Publication statusPublished - 2017 Apr 3

    Fingerprint

    bones
    anisotropy
    irradiation
    piezoelectricity
    healing
    collagens
    inclination
    wave propagation
    polarity
    transducers
    propagation

    ASJC Scopus subject areas

    • Physics and Astronomy (miscellaneous)

    Cite this

    Matsukawa, S., Makino, T., Mori, S., Koyama, D., Takayanagi, S., Mizuno, K., ... Matsukawa, M. (2017). Effect of anisotropy on stress-induced electrical potentials in bovine bone using ultrasound irradiation. Applied Physics Letters, 110(14), [143701]. https://doi.org/10.1063/1.4979599

    Effect of anisotropy on stress-induced electrical potentials in bovine bone using ultrasound irradiation. / Matsukawa, S.; Makino, T.; Mori, S.; Koyama, D.; Takayanagi, S.; Mizuno, K.; Yanagitani, Takahiko; Matsukawa, M.

    In: Applied Physics Letters, Vol. 110, No. 14, 143701, 03.04.2017.

    Research output: Contribution to journalArticle

    Matsukawa, S, Makino, T, Mori, S, Koyama, D, Takayanagi, S, Mizuno, K, Yanagitani, T & Matsukawa, M 2017, 'Effect of anisotropy on stress-induced electrical potentials in bovine bone using ultrasound irradiation', Applied Physics Letters, vol. 110, no. 14, 143701. https://doi.org/10.1063/1.4979599
    Matsukawa, S. ; Makino, T. ; Mori, S. ; Koyama, D. ; Takayanagi, S. ; Mizuno, K. ; Yanagitani, Takahiko ; Matsukawa, M. / Effect of anisotropy on stress-induced electrical potentials in bovine bone using ultrasound irradiation. In: Applied Physics Letters. 2017 ; Vol. 110, No. 14.
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