Effect of breath-hold on the responses of arterial blood pressure and cerebral blood velocity to isometric exercise

Hironori Watanabe, Takuro Washio, Shotaro Saito, Shigehiko Ogoh*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: The present study examined the effect of breath-hold without a Valsalva maneuver during isometric exercise on arterial blood pressure (ABP) and cerebral blood flow (CBF). Methods: Twenty healthy adults (15 men and five women) randomly performed only breath-hold without a Valsalva maneuver (BH), and an isometric handgrip exercise for 30 s at 40% of individual maximal voluntary contraction with continuous breathing (IHG) and with breath-hold without the Valsalva maneuver (IHG–BH). Mean ABP (MAP) and blood velocity in the middle (MCA Vmean) and posterior cerebral arteries (PCA Vmean) were continuously measured throughout each protocol. Results: MAP was elevated during the IHG–BH compared with IHG (P < 0.001) and BH (P = 0.001). Similarly, both MCA Vmean and PCA Vmean were higher during IHG–BH compared with IHG and BH (all P < 0.001). Moreover, the relative change in MAP from the baseline was correlated with that in both cerebral blood velocities during the BH (MCA Vmean: r = 0.739, P < 0.001 and PCA Vmean: r = 0.570, P = 0.009) and IHG–BH (MCA Vmean: r = 0.755, P < 0.001 and PCA Vmean: r = 0.617, P = 0.003) condition, but not the IHG condition (P = 0.154 and P = 0.306). Conclusion: These results indicate that during isometric exercise, a breath-hold enhances an exercise-induced increase in MAP and, consequently, MCA Vmean and PCA Vmean.

Original languageEnglish
Pages (from-to)157-168
Number of pages12
JournalEuropean Journal of Applied Physiology
Volume122
Issue number1
DOIs
Publication statusPublished - 2022 Jan
Externally publishedYes

Keywords

  • Cerebral hyperperfusion
  • Handgrip exercise
  • Hypertension
  • Middle cerebral artery
  • Posterior cerebral artery

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Public Health, Environmental and Occupational Health
  • Physiology (medical)

Fingerprint

Dive into the research topics of 'Effect of breath-hold on the responses of arterial blood pressure and cerebral blood velocity to isometric exercise'. Together they form a unique fingerprint.

Cite this