Effect of combined resistance and aerobic training on reactive hyperemia in men

Hiroshi Kawano, Kouhei Fujimoto, Mitsuru Higuchi, Motohiko Miyachi

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5 Citations (Scopus)


Reduced response to reactive hyperemia (RH) in the extremities reflects impaired endothelium-dependent vasodilation of the microvasculature. The aims of the present study were to determine whether resistance training and a combination of aerobic and resistance training increase the endothelial vasodilation of the forearm assessed by RH. A total of 39 young men were assigned to either high-intensity resistance training (HIR; six types of exercises, 80% 1RM × 10 repetitions × 3 sets, n = 14) or moderate-intensity resistance training (MIR; six types of exercises, 50% 1RM × 16 repetitions × 3 sets, n = 14) or a combination of high-intensity resistance training and moderate-intensity endurance training (COMBO; HIR and 60% maximal heart rate × 30 min, n = 11) groups. We measured forearm blood flow response to RH before and after 4 months of exercise intervention. All training groups increased maximal strength in all muscle groups tested (all P < 0.05). After 4 months of training, the forearm blood flow during RH increased significantly in the MIR and COMBO groups, from 57 ± 4 to 66 ± 7 ml/min per 100 ml tissue and from 59 ± 6 to 74 ± 8 ml/min per 100 ml tissue, respectively (both P < 0.05). There was no change in the response to RH in the HIR groups. In conclusion, the findings in this study demonstrate that combined resistance and aerobic training may affect the vasoreactivity response to RH in the forearm, but not resistance training alone.

Original languageEnglish
Pages (from-to)457-464
Number of pages8
JournalJournal of Physiological Sciences
Issue number6
Publication statusPublished - 2009 Nov



  • Blood flow
  • Combined training
  • Endothelial function
  • Exercise
  • Reactive hyperemia
  • Resistance training

ASJC Scopus subject areas

  • Physiology

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