Effect of electrochemically structured titanium alloys on cell morphology

S. Roy, Qi Bai Wu, S. Nouraei, S. Ngalim, M. Birch, A. McCaskie, H. Zhang, Tetsuya Osaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ti alloys are commonly used as dental and orthopaedic implants. It has been shown that surface topography can influence cell genesis, behaviour and growth. In this work we have electropolished and micro-patterned Ti-6Al-4V alloy to study the effect of surface topography on cell morphology. Electroetching was carried out in a flat cell under galvanostatic polarisation of 5.0 V and 9.0 V vs. SCE, using a 3.0 M H2SO4 - methanol electrolyte. Electropolishing conditions were achieved when the overpotential was 9.0 V. Micropatterning of Ti alloy substrates was carried out at the same potentials by etching through mask; a methanol stable SU-8 photoresist was used for this purpose. Human mesenchymal stem cells were seeded and grown on these substrates. It was found that surface nano and micro scale topography influenced cell numbers and morphology, respectively.

Original languageEnglish
Title of host publicationECS Transactions
Pages17-25
Number of pages9
Volume16
Edition38
DOIs
Publication statusPublished - 2009
EventBiological Nanostructures, Materials, and Applications - 214th ECS Meeting - Honolulu, HI
Duration: 2008 Oct 122008 Oct 17

Other

OtherBiological Nanostructures, Materials, and Applications - 214th ECS Meeting
CityHonolulu, HI
Period08/10/1208/10/17

Fingerprint

Titanium alloys
Surface topography
Methanol
Electrolytic polishing
Orthopedics
Substrates
Photoresists
Stem cells
Topography
Masks
Etching
Electrolytes
Polarization

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Roy, S., Wu, Q. B., Nouraei, S., Ngalim, S., Birch, M., McCaskie, A., ... Osaka, T. (2009). Effect of electrochemically structured titanium alloys on cell morphology. In ECS Transactions (38 ed., Vol. 16, pp. 17-25) https://doi.org/10.1149/1.3103806

Effect of electrochemically structured titanium alloys on cell morphology. / Roy, S.; Wu, Qi Bai; Nouraei, S.; Ngalim, S.; Birch, M.; McCaskie, A.; Zhang, H.; Osaka, Tetsuya.

ECS Transactions. Vol. 16 38. ed. 2009. p. 17-25.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Roy, S, Wu, QB, Nouraei, S, Ngalim, S, Birch, M, McCaskie, A, Zhang, H & Osaka, T 2009, Effect of electrochemically structured titanium alloys on cell morphology. in ECS Transactions. 38 edn, vol. 16, pp. 17-25, Biological Nanostructures, Materials, and Applications - 214th ECS Meeting, Honolulu, HI, 08/10/12. https://doi.org/10.1149/1.3103806
Roy S, Wu QB, Nouraei S, Ngalim S, Birch M, McCaskie A et al. Effect of electrochemically structured titanium alloys on cell morphology. In ECS Transactions. 38 ed. Vol. 16. 2009. p. 17-25 https://doi.org/10.1149/1.3103806
Roy, S. ; Wu, Qi Bai ; Nouraei, S. ; Ngalim, S. ; Birch, M. ; McCaskie, A. ; Zhang, H. ; Osaka, Tetsuya. / Effect of electrochemically structured titanium alloys on cell morphology. ECS Transactions. Vol. 16 38. ed. 2009. pp. 17-25
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