Effect of krill oil intake on human serum lipids - An open clinical trial

Shuichi Fukumoto, Yoshiyuki Katsumata, Kazuhiko Yoshikawa, Yoshiki Ito, Yuki Morimoto, Atsushi Kawase, Kazuhiro Sakaida, Naoko Suzuki, Kazuo Yamamoto, Tsuyoshi Takara, Kazunaga Yazawa

Research output: Contribution to journalArticle

Abstract

Objectives: The purpose of this study was to explore the effect of 8 weeks daily krill oil supplementation on serum triglyceride (TG) and lipid metabolism in the Japanese men and women. Methods: This clinical study was designed as an open test. The soft capsules of krill oil (1 g/day) was administered daily for 8 weeks to 139 healthy subjects. Blood samples, physical measurements and the dietary survey were taken at before/after intake of the krill oil. Results: The 78 subjects with more than 150 mg/dL TG levels were significant decrease in serum TG with krill oil intake. On the other hand, the 61 subjects with the standard value of TG levels were not changed in serum TG level with krill oil intake. Conclusions: The present study strongly suggests that krill oil is effective for reducing serum TG in the Japanese men and women, especially in subjects who have the borderline high or high fasting TG levels.

Original languageEnglish
Pages (from-to)679-685
Number of pages7
JournalJapanese Pharmacology and Therapeutics
Volume43
Issue number5
Publication statusPublished - 2015

Fingerprint

Euphausiacea
Oils
Triglycerides
Clinical Trials
Lipids
Serum
Lipid Metabolism
Capsules
Fasting
Healthy Volunteers

Keywords

  • Docosahexaenoic acid
  • Eicosapentaenoic acid
  • Krill oil
  • Omega-3 fatty acids
  • Triglyceride

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology

Cite this

Fukumoto, S., Katsumata, Y., Yoshikawa, K., Ito, Y., Morimoto, Y., Kawase, A., ... Yazawa, K. (2015). Effect of krill oil intake on human serum lipids - An open clinical trial. Japanese Pharmacology and Therapeutics, 43(5), 679-685.

Effect of krill oil intake on human serum lipids - An open clinical trial. / Fukumoto, Shuichi; Katsumata, Yoshiyuki; Yoshikawa, Kazuhiko; Ito, Yoshiki; Morimoto, Yuki; Kawase, Atsushi; Sakaida, Kazuhiro; Suzuki, Naoko; Yamamoto, Kazuo; Takara, Tsuyoshi; Yazawa, Kazunaga.

In: Japanese Pharmacology and Therapeutics, Vol. 43, No. 5, 2015, p. 679-685.

Research output: Contribution to journalArticle

Fukumoto, S, Katsumata, Y, Yoshikawa, K, Ito, Y, Morimoto, Y, Kawase, A, Sakaida, K, Suzuki, N, Yamamoto, K, Takara, T & Yazawa, K 2015, 'Effect of krill oil intake on human serum lipids - An open clinical trial', Japanese Pharmacology and Therapeutics, vol. 43, no. 5, pp. 679-685.
Fukumoto S, Katsumata Y, Yoshikawa K, Ito Y, Morimoto Y, Kawase A et al. Effect of krill oil intake on human serum lipids - An open clinical trial. Japanese Pharmacology and Therapeutics. 2015;43(5):679-685.
Fukumoto, Shuichi ; Katsumata, Yoshiyuki ; Yoshikawa, Kazuhiko ; Ito, Yoshiki ; Morimoto, Yuki ; Kawase, Atsushi ; Sakaida, Kazuhiro ; Suzuki, Naoko ; Yamamoto, Kazuo ; Takara, Tsuyoshi ; Yazawa, Kazunaga. / Effect of krill oil intake on human serum lipids - An open clinical trial. In: Japanese Pharmacology and Therapeutics. 2015 ; Vol. 43, No. 5. pp. 679-685.
@article{e93c67d49edc4d498c52c455695ada70,
title = "Effect of krill oil intake on human serum lipids - An open clinical trial",
abstract = "Objectives: The purpose of this study was to explore the effect of 8 weeks daily krill oil supplementation on serum triglyceride (TG) and lipid metabolism in the Japanese men and women. Methods: This clinical study was designed as an open test. The soft capsules of krill oil (1 g/day) was administered daily for 8 weeks to 139 healthy subjects. Blood samples, physical measurements and the dietary survey were taken at before/after intake of the krill oil. Results: The 78 subjects with more than 150 mg/dL TG levels were significant decrease in serum TG with krill oil intake. On the other hand, the 61 subjects with the standard value of TG levels were not changed in serum TG level with krill oil intake. Conclusions: The present study strongly suggests that krill oil is effective for reducing serum TG in the Japanese men and women, especially in subjects who have the borderline high or high fasting TG levels.",
keywords = "Docosahexaenoic acid, Eicosapentaenoic acid, Krill oil, Omega-3 fatty acids, Triglyceride",
author = "Shuichi Fukumoto and Yoshiyuki Katsumata and Kazuhiko Yoshikawa and Yoshiki Ito and Yuki Morimoto and Atsushi Kawase and Kazuhiro Sakaida and Naoko Suzuki and Kazuo Yamamoto and Tsuyoshi Takara and Kazunaga Yazawa",
year = "2015",
language = "English",
volume = "43",
pages = "679--685",
journal = "Japanese Pharmacology and Therapeutics",
issn = "0386-3603",
publisher = "Life Science Publishing Co. Ltd",
number = "5",

}

TY - JOUR

T1 - Effect of krill oil intake on human serum lipids - An open clinical trial

AU - Fukumoto, Shuichi

AU - Katsumata, Yoshiyuki

AU - Yoshikawa, Kazuhiko

AU - Ito, Yoshiki

AU - Morimoto, Yuki

AU - Kawase, Atsushi

AU - Sakaida, Kazuhiro

AU - Suzuki, Naoko

AU - Yamamoto, Kazuo

AU - Takara, Tsuyoshi

AU - Yazawa, Kazunaga

PY - 2015

Y1 - 2015

N2 - Objectives: The purpose of this study was to explore the effect of 8 weeks daily krill oil supplementation on serum triglyceride (TG) and lipid metabolism in the Japanese men and women. Methods: This clinical study was designed as an open test. The soft capsules of krill oil (1 g/day) was administered daily for 8 weeks to 139 healthy subjects. Blood samples, physical measurements and the dietary survey were taken at before/after intake of the krill oil. Results: The 78 subjects with more than 150 mg/dL TG levels were significant decrease in serum TG with krill oil intake. On the other hand, the 61 subjects with the standard value of TG levels were not changed in serum TG level with krill oil intake. Conclusions: The present study strongly suggests that krill oil is effective for reducing serum TG in the Japanese men and women, especially in subjects who have the borderline high or high fasting TG levels.

AB - Objectives: The purpose of this study was to explore the effect of 8 weeks daily krill oil supplementation on serum triglyceride (TG) and lipid metabolism in the Japanese men and women. Methods: This clinical study was designed as an open test. The soft capsules of krill oil (1 g/day) was administered daily for 8 weeks to 139 healthy subjects. Blood samples, physical measurements and the dietary survey were taken at before/after intake of the krill oil. Results: The 78 subjects with more than 150 mg/dL TG levels were significant decrease in serum TG with krill oil intake. On the other hand, the 61 subjects with the standard value of TG levels were not changed in serum TG level with krill oil intake. Conclusions: The present study strongly suggests that krill oil is effective for reducing serum TG in the Japanese men and women, especially in subjects who have the borderline high or high fasting TG levels.

KW - Docosahexaenoic acid

KW - Eicosapentaenoic acid

KW - Krill oil

KW - Omega-3 fatty acids

KW - Triglyceride

UR - http://www.scopus.com/inward/record.url?scp=84938079836&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938079836&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84938079836

VL - 43

SP - 679

EP - 685

JO - Japanese Pharmacology and Therapeutics

JF - Japanese Pharmacology and Therapeutics

SN - 0386-3603

IS - 5

ER -