Effect of krill oil intake on human serum lipids - An open clinical trial

Shuichi Fukumoto, Yoshiyuki Katsumata, Kazuhiko Yoshikawa, Yoshiki Ito, Yuki Morimoto, Atsushi Kawase, Kazuhiro Sakaida, Naoko Suzuki, Kazuo Yamamoto, Tsuyoshi Takara, Kazunaga Yazawa

Research output: Contribution to journalArticle

Abstract

Objectives: The purpose of this study was to explore the effect of 8 weeks daily krill oil supplementation on serum triglyceride (TG) and lipid metabolism in the Japanese men and women. Methods: This clinical study was designed as an open test. The soft capsules of krill oil (1 g/day) was administered daily for 8 weeks to 139 healthy subjects. Blood samples, physical measurements and the dietary survey were taken at before/after intake of the krill oil. Results: The 78 subjects with more than 150 mg/dL TG levels were significant decrease in serum TG with krill oil intake. On the other hand, the 61 subjects with the standard value of TG levels were not changed in serum TG level with krill oil intake. Conclusions: The present study strongly suggests that krill oil is effective for reducing serum TG in the Japanese men and women, especially in subjects who have the borderline high or high fasting TG levels.

Original languageEnglish
Pages (from-to)679-685
Number of pages7
JournalJapanese Pharmacology and Therapeutics
Volume43
Issue number5
Publication statusPublished - 2015

Keywords

  • Docosahexaenoic acid
  • Eicosapentaenoic acid
  • Krill oil
  • Omega-3 fatty acids
  • Triglyceride

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology

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  • Cite this

    Fukumoto, S., Katsumata, Y., Yoshikawa, K., Ito, Y., Morimoto, Y., Kawase, A., Sakaida, K., Suzuki, N., Yamamoto, K., Takara, T., & Yazawa, K. (2015). Effect of krill oil intake on human serum lipids - An open clinical trial. Japanese Pharmacology and Therapeutics, 43(5), 679-685.