Effect of Mg on surface roughness and protein content of protein-apatite composite layers

Yuusuke Ishikawa, Nao Kondo, Yu Sogo, Atsuo Ito, Eiji Uchimura, Ayako Oyane, Tadao Ohno, Atsushi Yamazaki, Takashi Ushida, Katsuko Furukawa

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    Fibronectin (FN)-apatite composite layers were formed on a hydroxyapatite (HAP) ceramic using supersaturated calcium phosphate (CP) solutions. The surface roughness of the composite layer could be controllable by changing the magnesium (Mg) concentration in the CP solution. The higher the Mg concentration, the smaller the apatite crystals in the layer were. The thickness of the layer formed in the CP solution containing 1.5 mM Mg decreased to 68% that formed in the Mg-free CP solution. The amount of FN immobilized in the layer was almost constant regardless of Mg concentration in the CP solution in the range from 0 to 1.5 mM. The results of the present study revealed that a thin FN-apatite composite layer with a smooth surface and a high protein content is formed in a CP solution at a Mg concentration of 1.5 mM.

    Original languageEnglish
    Pages (from-to)85-88
    Number of pages4
    JournalKey Engineering Materials
    Volume309-311 I
    Publication statusPublished - 2006

    Fingerprint

    Apatites
    Apatite
    Calcium phosphate
    Magnesium
    Membrane Proteins
    Surface roughness
    Proteins
    Composite materials
    Fibronectins
    Durapatite
    Hydroxyapatite
    calcium phosphate
    Crystals

    Keywords

    • Composite layer
    • Fibronectin
    • Hydroxyapatite
    • Magnesium
    • Surface roughness

    ASJC Scopus subject areas

    • Ceramics and Composites
    • Chemical Engineering (miscellaneous)

    Cite this

    Ishikawa, Y., Kondo, N., Sogo, Y., Ito, A., Uchimura, E., Oyane, A., ... Furukawa, K. (2006). Effect of Mg on surface roughness and protein content of protein-apatite composite layers. Key Engineering Materials, 309-311 I, 85-88.

    Effect of Mg on surface roughness and protein content of protein-apatite composite layers. / Ishikawa, Yuusuke; Kondo, Nao; Sogo, Yu; Ito, Atsuo; Uchimura, Eiji; Oyane, Ayako; Ohno, Tadao; Yamazaki, Atsushi; Ushida, Takashi; Furukawa, Katsuko.

    In: Key Engineering Materials, Vol. 309-311 I, 2006, p. 85-88.

    Research output: Contribution to journalArticle

    Ishikawa, Y, Kondo, N, Sogo, Y, Ito, A, Uchimura, E, Oyane, A, Ohno, T, Yamazaki, A, Ushida, T & Furukawa, K 2006, 'Effect of Mg on surface roughness and protein content of protein-apatite composite layers', Key Engineering Materials, vol. 309-311 I, pp. 85-88.
    Ishikawa Y, Kondo N, Sogo Y, Ito A, Uchimura E, Oyane A et al. Effect of Mg on surface roughness and protein content of protein-apatite composite layers. Key Engineering Materials. 2006;309-311 I:85-88.
    Ishikawa, Yuusuke ; Kondo, Nao ; Sogo, Yu ; Ito, Atsuo ; Uchimura, Eiji ; Oyane, Ayako ; Ohno, Tadao ; Yamazaki, Atsushi ; Ushida, Takashi ; Furukawa, Katsuko. / Effect of Mg on surface roughness and protein content of protein-apatite composite layers. In: Key Engineering Materials. 2006 ; Vol. 309-311 I. pp. 85-88.
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    AU - Oyane, Ayako

    AU - Ohno, Tadao

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