TY - JOUR
T1 - Effect of spore-bearing lactic acid-forming bacteria (Bacillus coagulans SANK 70258) administration on the intestinal environment, defecation frequency, fecal characteristics and dermal characteristics in humans and rats
AU - Ara, Katsutoshi
AU - Meguro, Shinichi
AU - Hase, Tadasi
AU - Tokimitsu, Ichirou
AU - Otsuji, Kazuya
AU - Kawai, Shuji
AU - Ito, Susumu
AU - Iino, Hisakazu
N1 - Funding Information:
EXPLANATION OF ABBREVIATIONS: CIP, International Potato Center (Centro Interuacional de la Papa), and a herbarium code used by this organization for their herbarium in La Molina, Peru CGN, Centre for Genetic Resources, The Netherlands INIA, Instituto Nacional de Investigacion Agraria (National Institute for Agrarian Research), Peruvian Ministry of Agriculture IPK, Institut fitr Pflanzengenetik und Kulturpflanzenforschung, Gater-sleben, Grog Ltisewitz, Germany MOL, Herbario Weberbauer, Departamento de Biologia, Secci6n Botfinica, Universidad Nacional Agraria, La Molina, Peru NRSP-6, National Research Support Program-6, Sturgeon Bay, Wiscon-sin, USA (the United States potato genebank, formerly called the Inter-Regional Potato Introduction Project, IR-1) PTIS, Herbarium of NRSP-6 WAG, National Herbarium Nederland, Wageningen University branch, Wageningen, The Netherlands de papa silvestre descrita, muchas de las cuales ailn no est~n conservadas en bancos gen6ticos. Este articulo consigna los resultados de la segunda de una serie de cinco expediciones planificadas de recolecci6n en el Peril. Se colect5 en los departamentos de Ancash, Huan-cavelica, La Libertad y Lima, entre el 8 de marzo y el 25 de abril de 1999. Fueron la continuaci6n de colecciones realizadas en 1998 en el sur del Peril, en los departa-mentos de Apurimac, Arequipa, Cusco, Moquegua, Puno y Tacna. Recolectamos 101 accesiones de germoplasma, incluyendo las primeras colecciones de germoplasma de las siguientes 22 taxa de Solanum: Solanum amayanum, S. anamatophilum, S. arahuayum (perdida al incre-mentar germoplasma), S. augustii, S. bill-hookeri, S. cantense, S. chavinense, S. chomatophilum var. subni-vale, S. chrysoflorum, S. gracil~frons, S. hapalosum, S. huarochiriense, S. hypacrarthrum, S.jalcae, S. moniliforme, S. multiinterruptum f . longipilosum, S. multiin-terruptum var. machaytambinum, S. peloquinianum, S. rhombilanceolatum, S. simplicissimum, S. taulisense (perdida al incrementar germoplasma) y S. wittmackii. Adem~, colectamos una especie poca colectada: S. has-tiforme (tres colecciones). La taxonomia aqul usada es la del planeamiento la expedici6n que fue comparada con el nuevo tratamiento de papas silvestres peruanas publicado por Carlos Ochoa en 1999. Este articulo informa sobre la colecciSn y la identificaci6n de nuevas especies de las colecciones de 1999 y de la conservaci6n y supervivencia del germoplasma de las colecciones de 1998 y 1999. Asimismo, se proporciona el conteo de cro-mosomas de 134 accesiones de las expediciones de 1998 y 1999, incluido el primer reporte de S. megis-tacrolobum subsp, purpureum (2n = 2x = 24), S. multi-interruptum var. multiinterruptum f. albO"lorum (2n = 2x = 24) y S. velardei (2n = 2x =24); tambi~n infor-mamos sobre el primer conteo de triploide de una acce-siSn de S. immite.
PY - 2002
Y1 - 2002
N2 - The effects of spore-bearing lactic acid-forming bacteria (Bacillus coagulans SANK 70258) on intestinal flora and decomposition products in the intestine, as well as on various dermal characteristics were determined in healthy humans and rats. Improvement of fecal shape, change of fecal color from dark brown to yellowish brown, decrease of fecal odor and fecal pH and an increase in defecation frequency in persons whose defecation frequency was relatively low were observed after administration. The number of intestinal bifidobacteria significantly (p < 0.05) increased, whereas the number of intestinal Clostridium perfringens significantly (p < 0.05) decreased after administration compared with the values before the intake. The concentrations of intestinal ammonia, indole and p-cresol decreased. The activities of β-glucuronidase and tryptophanase decreased significantly compared with the levels during the control period (p < 0.05). The spore-bearing lactic acid-forming bacilli group was given B. coagulans SANK 70258, while kept on a basic diet adjusted to 60% protein. Protein was supplied by casein. After removing back hair, the rats were exposed to radiation of UV-B 0.5 MED once a day. Two weeks after the start of radiation, measurements were made for the number of exanthema (the number of flare and papula). The number of exanthema decreased as constipation alleviated as a result of the intake of B. coagulans SANK 70258. In experiment 2, improvement of fecal shape, change of fecal color from dark brown to yellowish brown, decrease of fecal odor, the fecal pH and increase in defecation frequency of persons whose frequency was relatively low were observed after administration. The number of intestinal bifidobacteria significantly (p < 0.05) increased, whereas the number of intestinal C. perfringens significantly (p < 0.05) decreased after administration compared with the values before the intake. The concentrations of intestinal ammonia, indole and p-cresol content decreased. The activity of β-glucuronidase and tryptophanase decreased significantly (p < 0.05) compared with the levels during the control period. The number of comedones decreased as constipation was alleviated as a result of the intake of B. coagulans SANK 70258. These results indicate that the administration of B. coagulans SANK 70258 improves the intestinal environment, defecation frequency, fecal characteristics and dermal characteristics.
AB - The effects of spore-bearing lactic acid-forming bacteria (Bacillus coagulans SANK 70258) on intestinal flora and decomposition products in the intestine, as well as on various dermal characteristics were determined in healthy humans and rats. Improvement of fecal shape, change of fecal color from dark brown to yellowish brown, decrease of fecal odor and fecal pH and an increase in defecation frequency in persons whose defecation frequency was relatively low were observed after administration. The number of intestinal bifidobacteria significantly (p < 0.05) increased, whereas the number of intestinal Clostridium perfringens significantly (p < 0.05) decreased after administration compared with the values before the intake. The concentrations of intestinal ammonia, indole and p-cresol decreased. The activities of β-glucuronidase and tryptophanase decreased significantly compared with the levels during the control period (p < 0.05). The spore-bearing lactic acid-forming bacilli group was given B. coagulans SANK 70258, while kept on a basic diet adjusted to 60% protein. Protein was supplied by casein. After removing back hair, the rats were exposed to radiation of UV-B 0.5 MED once a day. Two weeks after the start of radiation, measurements were made for the number of exanthema (the number of flare and papula). The number of exanthema decreased as constipation alleviated as a result of the intake of B. coagulans SANK 70258. In experiment 2, improvement of fecal shape, change of fecal color from dark brown to yellowish brown, decrease of fecal odor, the fecal pH and increase in defecation frequency of persons whose frequency was relatively low were observed after administration. The number of intestinal bifidobacteria significantly (p < 0.05) increased, whereas the number of intestinal C. perfringens significantly (p < 0.05) decreased after administration compared with the values before the intake. The concentrations of intestinal ammonia, indole and p-cresol content decreased. The activity of β-glucuronidase and tryptophanase decreased significantly (p < 0.05) compared with the levels during the control period. The number of comedones decreased as constipation was alleviated as a result of the intake of B. coagulans SANK 70258. These results indicate that the administration of B. coagulans SANK 70258 improves the intestinal environment, defecation frequency, fecal characteristics and dermal characteristics.
KW - Bifidobacteria
KW - Comedones
KW - Dermal characteristics
KW - Intestinal environment
KW - Intestinal flora
KW - Spore-forming lactobacillus
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U2 - 10.1080/089106002760002694
DO - 10.1080/089106002760002694
M3 - Article
AN - SCOPUS:0036224276
VL - 14
SP - 4
EP - 13
JO - Microbial Ecology in Health and Disease
JF - Microbial Ecology in Health and Disease
SN - 0891-060X
IS - 1
ER -