Effects of acute endurance exercise performed in the morning and evening on inflammatory cytokine and metabolic hormone responses

Hyeonki Kim, Masayuki Konishi, Masaki Takahashi, Hiroki Tabata, Naoya Endo, Shigeharu Numao, Sun Kyoung Lee, Young Hak Kim, Katsuhiko Suzuki, Shizuo Sakamoto

Research output: Contribution to journalArticle

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Abstract

Purpose: To compare the effects of endurance exercise performed in the morning and evening on inflammatory cytokine responses in young men. Methods: Fourteen healthy male participants aged 24.3 ± 0.8 years (mean ± standard error) performed endurance exercise in the morning (0900-1000 h) on one day and then in the evening (1700-1800 h) on another day with an interval of at least 1 week between each trial. In both the morning and evening trials, the participants walked for 60 minutes at approximately 60% of the maximal oxygen uptake (VO2max) on a treadmill. Blood samples were collected to determine hormones and inflammatory cytokines at pre-exercise, immediately post exercise, and 2 h post exercise. Results: Plasma interleukin (IL)-6 and adrenaline concentrations were significantly higher immediately after exercise in the evening trial than in the morning trial (P <0.01, both). Serum free fatty acids concentrations were significantly higher in the evening trial than in the morning trial at 2 h after exercise (P <0.05). Furthermore, a significant correlation was observed between the levels of IL-6 immediately post-exercise and free fatty acids 2 h post-exercise in the evening (r = 0.68, P <0.01). Conclusions: These findings suggest that the effect of acute endurance exercise in the evening enhances the plasma IL-6 and adrenaline concentrations compared to that in the morning. In addition, IL-6 was involved in increasing free fatty acids, suggesting that the evening is more effective for exercise-induced lipolysis compared with the morning.

Original languageEnglish
Article numbere0137567
JournalPLoS One
Volume10
Issue number9
DOIs
Publication statusPublished - 2015 Sep 9

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Interleukin-6
Durability
exercise
cytokines
Nonesterified Fatty Acids
hormones
Hormones
Exercise
Cytokines
Epinephrine
interleukin-6
Plasmas
Exercise equipment
free fatty acids
Blood
epinephrine
Oxygen
Lipolysis
exercise equipment
lipolysis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Effects of acute endurance exercise performed in the morning and evening on inflammatory cytokine and metabolic hormone responses. / Kim, Hyeonki; Konishi, Masayuki; Takahashi, Masaki; Tabata, Hiroki; Endo, Naoya; Numao, Shigeharu; Lee, Sun Kyoung; Kim, Young Hak; Suzuki, Katsuhiko; Sakamoto, Shizuo.

In: PLoS One, Vol. 10, No. 9, e0137567, 09.09.2015.

Research output: Contribution to journalArticle

Kim, Hyeonki ; Konishi, Masayuki ; Takahashi, Masaki ; Tabata, Hiroki ; Endo, Naoya ; Numao, Shigeharu ; Lee, Sun Kyoung ; Kim, Young Hak ; Suzuki, Katsuhiko ; Sakamoto, Shizuo. / Effects of acute endurance exercise performed in the morning and evening on inflammatory cytokine and metabolic hormone responses. In: PLoS One. 2015 ; Vol. 10, No. 9.
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