Effects of aerobic exercise alone on lipids in healthy east asians: A systematic review and meta-analysis

Yutaka Igarashi, Nobuhiko Akazawa, Seiji Maeda

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Aim: The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. Methods: The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥ 40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group-mean value at baseline in the exercise group)-(mean value at post-intervention in the control group-mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. Results: The meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, -5.8 mg/dL; TG, -13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I2 =45.1%; TC, I2 =56.2%). When trials were limited to those involving moderate-intensity exercise (55% – 69% of the maximum heart rate) or an exercise volume ≥ 150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity. Conclusions: The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥ 150 min/week.

Original languageEnglish
Pages (from-to)488-503
Number of pages16
JournalJournal of Atherosclerosis and Thrombosis
Volume26
Issue number5
DOIs
Publication statusPublished - 2019
Externally publishedYes

Keywords

  • Form of exercise
  • Heterogeneity
  • Randomized controlled trial

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Biochemistry, medical

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