Effects of an upstream DNA curvature on the strength of HSV thymidine kinase promoter.

Takashi Ohyama, Y. Kadokawa, Y. Hirota

Research output: Contribution to journalArticle

Abstract

The effect of an upstream DNA curvature on the strength of the herpes simplex virus thymidine kinase (TK) promoter was investigated by employing luciferase assay. A set of double-stranded oligonucleotides, each with an unique DNA configuration, were synthesized and substituted into an upstream region of the promoter. It was revealed from the assay that both plane and space curves exerted a negative influence upon the strength of the promoter.

Original languageEnglish
Pages (from-to)67-68
Number of pages2
JournalNucleic acids symposium series
Issue number34
Publication statusPublished - 1995
Externally publishedYes

Fingerprint

Thymidine Kinase
DNA
Simplexvirus
Luciferases
Genetic Promoter Regions
Oligonucleotides

Cite this

Effects of an upstream DNA curvature on the strength of HSV thymidine kinase promoter. / Ohyama, Takashi; Kadokawa, Y.; Hirota, Y.

In: Nucleic acids symposium series, No. 34, 1995, p. 67-68.

Research output: Contribution to journalArticle

@article{436b14fb0e0a4c6da7cb44db3c23b36e,
title = "Effects of an upstream DNA curvature on the strength of HSV thymidine kinase promoter.",
abstract = "The effect of an upstream DNA curvature on the strength of the herpes simplex virus thymidine kinase (TK) promoter was investigated by employing luciferase assay. A set of double-stranded oligonucleotides, each with an unique DNA configuration, were synthesized and substituted into an upstream region of the promoter. It was revealed from the assay that both plane and space curves exerted a negative influence upon the strength of the promoter.",
author = "Takashi Ohyama and Y. Kadokawa and Y. Hirota",
year = "1995",
language = "English",
pages = "67--68",
journal = "Nucleic acids symposium series",
issn = "0261-3166",
publisher = "Information Retrieval",
number = "34",

}

TY - JOUR

T1 - Effects of an upstream DNA curvature on the strength of HSV thymidine kinase promoter.

AU - Ohyama, Takashi

AU - Kadokawa, Y.

AU - Hirota, Y.

PY - 1995

Y1 - 1995

N2 - The effect of an upstream DNA curvature on the strength of the herpes simplex virus thymidine kinase (TK) promoter was investigated by employing luciferase assay. A set of double-stranded oligonucleotides, each with an unique DNA configuration, were synthesized and substituted into an upstream region of the promoter. It was revealed from the assay that both plane and space curves exerted a negative influence upon the strength of the promoter.

AB - The effect of an upstream DNA curvature on the strength of the herpes simplex virus thymidine kinase (TK) promoter was investigated by employing luciferase assay. A set of double-stranded oligonucleotides, each with an unique DNA configuration, were synthesized and substituted into an upstream region of the promoter. It was revealed from the assay that both plane and space curves exerted a negative influence upon the strength of the promoter.

UR - http://www.scopus.com/inward/record.url?scp=0029433335&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029433335&partnerID=8YFLogxK

M3 - Article

C2 - 8841555

AN - SCOPUS:0029433335

SP - 67

EP - 68

JO - Nucleic acids symposium series

JF - Nucleic acids symposium series

SN - 0261-3166

IS - 34

ER -