Effects of astaxanthin in obese mice fed a high-fat diet

Mayumi Ikeuchi, Tomoyuki Koyama, Jiro Takahashi, Kazunaga Yazawa

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

Astaxanthin is a natural antioxidant carotenoid that occurs in a wide variety of living organisms. We investigated the effects of astaxanthin supplementation in obese mice fed a high-fat diet. Astaxanthin inhibited the increases in body weight and weight of adipose tissue that result from feeding a high-fat diet. In addition, astaxanthin reduced liver weight, liver triglyceride, plasma triglyceride, and total cholesterol. These results suggest that astaxanthin might be of value in reducing the likelihood of obesity and metabolic syndrome in affluent societies.

Original languageEnglish
Pages (from-to)893-899
Number of pages7
JournalBioscience, Biotechnology and Biochemistry
Volume71
Issue number4
DOIs
Publication statusPublished - 2007
Externally publishedYes

Fingerprint

Obese Mice
astaxanthin
High Fat Diet
high fat diet
Nutrition
Oils and fats
Liver
Fats
Cholesterol
mice
Antioxidants
Tissue
Plasmas
Triglycerides
triacylglycerols
Weights and Measures
liver
metabolic syndrome
Carotenoids
adipose tissue

Keywords

  • Astaxanthin
  • High-fat diet
  • Obesity

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Food Science

Cite this

Effects of astaxanthin in obese mice fed a high-fat diet. / Ikeuchi, Mayumi; Koyama, Tomoyuki; Takahashi, Jiro; Yazawa, Kazunaga.

In: Bioscience, Biotechnology and Biochemistry, Vol. 71, No. 4, 2007, p. 893-899.

Research output: Contribution to journalArticle

Ikeuchi, M, Koyama, T, Takahashi, J & Yazawa, K 2007, 'Effects of astaxanthin in obese mice fed a high-fat diet', Bioscience, Biotechnology and Biochemistry, vol. 71, no. 4, pp. 893-899. https://doi.org/10.1271/bbb.60521
Ikeuchi, Mayumi ; Koyama, Tomoyuki ; Takahashi, Jiro ; Yazawa, Kazunaga. / Effects of astaxanthin in obese mice fed a high-fat diet. In: Bioscience, Biotechnology and Biochemistry. 2007 ; Vol. 71, No. 4. pp. 893-899.
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