Effects of astaxanthin in obese mice fed a high-fat diet

Mayumi Ikeuchi, Tomoyuki Koyama, Jiro Takahashi, Kazunaga Yazawa

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

Astaxanthin is a natural antioxidant carotenoid that occurs in a wide variety of living organisms. We investigated the effects of astaxanthin supplementation in obese mice fed a high-fat diet. Astaxanthin inhibited the increases in body weight and weight of adipose tissue that result from feeding a high-fat diet. In addition, astaxanthin reduced liver weight, liver triglyceride, plasma triglyceride, and total cholesterol. These results suggest that astaxanthin might be of value in reducing the likelihood of obesity and metabolic syndrome in affluent societies.

Original languageEnglish
Pages (from-to)893-899
Number of pages7
JournalBioscience, Biotechnology and Biochemistry
Volume71
Issue number4
DOIs
Publication statusPublished - 2007
Externally publishedYes

Keywords

  • Astaxanthin
  • High-fat diet
  • Obesity

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Food Science

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