Effects of high-intensity endurance exercise on epidermal barriers against microbial invasion

Nobuhiko Eda, Kazuhiro Shimizu, Satomi Suzuki, Eunjae Lee, Takao Akama

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

For athletes, preventing infectious disease on skin is important. Examination measurement of epidermal barriers could provide valuable information on the risk of skin infections. The aim of this study was to determine the effects of high-intensity endurance exercise on epidermal barriers. Six healthy adult males (age; 22.3 ± 1.6 years) performed bicycle exercise at 75%HRmax for 60 min from 18:30 to 19:30. Skin surface samples were measured 18:30 (pre), 19:30 (post), 20:30 (60 min), and 21:30 (120 min). Secretory immunoglobulin A (SIgA) and human β-defensin 2 (HBD-2) concentrations were measured using an enzyme-linked immunosorbent assay (ELISA). SIgA concentration at pre was significantly higher than at post, 60 min and 120 min (p < 0.05). HBD-2 concentration at post and 120 min was significantly higher than at pre (p < 0.05). Moisture content of the stratum corneum was significantly higher at post than at pre, 60 min, and 120 min (p < 0.05). On the chest, moisture content of the stratum corneum was significantly lower at 120 min than at pre (p < 0.05). The number of staphylococci was significantly higher at post than at pre (p < 0.05), and tended to be higher at 60 min than at pre on the chest (p = 0.08). High-intensity endurance exercise might depress the immune barrier and physical barrier and enhance the risk of skin infection. On the other hand, the biochemical barrier increases after exercise, and our findings suggest that this barrier might supplement the compromised function of other skin barriers.

Original languageEnglish
Pages (from-to)44-51
Number of pages8
JournalJournal of Sports Science and Medicine
Volume12
Issue number1
Publication statusPublished - 2013 Mar

Fingerprint

Exercise
Secretory Immunoglobulin A
Skin
Cornea
Infectious Skin Diseases
Thorax
Defensins
Architectural Accessibility
Infection
Staphylococcus
Athletes
Enzyme-Linked Immunosorbent Assay

Keywords

  • Athletes
  • Beta-defensins
  • Secretory immunoglobulin a
  • Skin infections
  • Staphylococcus

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Effects of high-intensity endurance exercise on epidermal barriers against microbial invasion. / Eda, Nobuhiko; Shimizu, Kazuhiro; Suzuki, Satomi; Lee, Eunjae; Akama, Takao.

In: Journal of Sports Science and Medicine, Vol. 12, No. 1, 03.2013, p. 44-51.

Research output: Contribution to journalArticle

Eda, Nobuhiko ; Shimizu, Kazuhiro ; Suzuki, Satomi ; Lee, Eunjae ; Akama, Takao. / Effects of high-intensity endurance exercise on epidermal barriers against microbial invasion. In: Journal of Sports Science and Medicine. 2013 ; Vol. 12, No. 1. pp. 44-51.
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