Effects of immersion in cholesterol-lipid solution on the tensile and fatigue properties of elastomeric polymers for blood pump applications

K. Hayashi, T. Matsuda, H. Takano, Mitsuo Umezu

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Tensile and fatigue properties were studied on three kinds of segmented polyether polyurethanes developed for blood pump applications. To study the effects of plasma constitutents, specimens were immersed in a cholesterol-lipid solution whose composition is similar to that of plasma. The results obtained were compared with those observed in a saline solution which had been reported previously. Immersion in the cholesterol-lipid solution has influence on the mechanical properties of Toyobo TM% polyurethane and Avcothane 51: Its effect is enhanced by cyclic deformation. Cholesterol-lipids change the mechanical characteristics of Avcothane 51 more remarkably than those of Toyobo TM5 polyurethane possibly because the former contains about 10% silicone. On the other hand, there is little effect of the constituents of the cholesterol-lipid solution on the static and dynamic mechanical properties of Biomer, although moisture and cyclic deformation have some influence on the mechanical characteristics.

Original languageEnglish
Pages (from-to)939-951
Number of pages13
JournalJournal of Biomedical Materials Research
Volume18
Issue number8
Publication statusPublished - 1984 Oct
Externally publishedYes

Fingerprint

Cholesterol
Lipids
Polyurethanes
Polymers
Blood
Pumps
Fatigue of materials
Plasmas
Mechanical properties
Polyethers
Silicones
Sodium Chloride
Moisture
elastomeric
Chemical analysis
Avcothane

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials

Cite this

Effects of immersion in cholesterol-lipid solution on the tensile and fatigue properties of elastomeric polymers for blood pump applications. / Hayashi, K.; Matsuda, T.; Takano, H.; Umezu, Mitsuo.

In: Journal of Biomedical Materials Research, Vol. 18, No. 8, 10.1984, p. 939-951.

Research output: Contribution to journalArticle

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