Effects of lifestyle modification on central blood pressure in overweight and obese men

Ryota Higashino, Asako Miyaki, Hiroshi Kumagai, Youngju Choi, Nobuhiko Akazawa, Song Gyu Ra, Yoko Tanabe, Miki Eto, Rina So, Kiyoji Tanaka, Ryuichi Ajisaka, Seiji Maeda

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Objective It has recently been recognized that increased central blood pressure is a predictor of cardiovascular disease. Central blood pressure is higher in obese individuals than in nonobese individuals. However, the effect of lifestyle modification on central systolic blood pressure in obese individuals is unclear. The aim of this study was to determine whether lifestyle modification decreases central blood pressure in overweight and obese men. Methods Thirty-nine overweight and obese men (age, 49±2 years; BMI, 30±1 kg/m2) were recruited into our study. We measured central systolic blood pressure and brachial-ankle pulse wave velocity (baPWV), an index of arterial stiffness, before and after a 12-week lifestyle modification that included aerobic exercise and dietary modification. Results After the 12-week program, body mass, BMI, and waist circumstance decreased significantly. Central systolic blood pressure and baPWV were significantly decreased after the lifestyle modification in overweight and obese men. Furthermore, there was a significant correlation between the lifestyle modification-induced change in central systolic blood pressure and that in baPWV. Conclusion This study showed for the first time that lifestyle modification-induced weight loss decreases central systolic blood pressure in overweight and obese men. The decrease in central systolic blood pressure was associated with the reduction in arterial stiffness. These results suggest that lifestyle modification-induced reduction in arterial stiffness may contribute toward the decreased central systolic blood pressure in overweight and obese men. Blood Press Monit 18:311-315

Original languageEnglish
Pages (from-to)311-315
Number of pages5
JournalBlood Pressure Monitoring
Volume18
Issue number6
DOIs
Publication statusPublished - 2013 Dec
Externally publishedYes

Keywords

  • Arterial stiffness
  • Central blood pressure
  • Obesity
  • Weight loss

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Assessment and Diagnosis
  • Advanced and Specialised Nursing

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