Effects of microinjection of melatonin into various brain regions of Japanese quail on locomotor activity and body temperature

Keiko Nakahara, Takanori Kawano, Kunio Shiota, Noboru Murakami

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We previously reported that peripheral administration of melatonin resulted in simultaneous decreases in locomotor activity and body temperature in the Japanese quail. To examine the site of these melatonin-induced effects, we performed microinjection of melatonin into various brain regions of the Japanese quail. On the basis of the injection site the effects of melatonin were dissociated into four groups: decrease in only body temperature, decrease in only locomotor activity, decrease in both body temperature and locomotor activity, and a change in neither. The decrease in only body temperature was observed when melatonin was injected into areas of the diencephalon including the thalamus and hypothalamus, and the decrease in only locomotor activity was observed when melatonin was injected close to the nuclei septalis medialis and septalis lateralis. These results suggest that melatonin-induced decreases in body temperature and locomotor activity occur by melatonin acting at discrete sites in the brain.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalNeuroscience Letters
Volume345
Issue number2
DOIs
Publication statusPublished - 2003 Jul 17
Externally publishedYes

Fingerprint

Coturnix
Microinjections
Melatonin
Locomotion
Body Temperature
Brain
Diencephalon
Thalamus
Hypothalamus
Injections

Keywords

  • Body temperature
  • Circadian rhythm
  • Japanese quail
  • Locomotor activity
  • Melatonin

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effects of microinjection of melatonin into various brain regions of Japanese quail on locomotor activity and body temperature. / Nakahara, Keiko; Kawano, Takanori; Shiota, Kunio; Murakami, Noboru.

In: Neuroscience Letters, Vol. 345, No. 2, 17.07.2003, p. 117-120.

Research output: Contribution to journalArticle

Nakahara, Keiko ; Kawano, Takanori ; Shiota, Kunio ; Murakami, Noboru. / Effects of microinjection of melatonin into various brain regions of Japanese quail on locomotor activity and body temperature. In: Neuroscience Letters. 2003 ; Vol. 345, No. 2. pp. 117-120.
@article{77b7aceed296472193160ed4e1dcd1e3,
title = "Effects of microinjection of melatonin into various brain regions of Japanese quail on locomotor activity and body temperature",
abstract = "We previously reported that peripheral administration of melatonin resulted in simultaneous decreases in locomotor activity and body temperature in the Japanese quail. To examine the site of these melatonin-induced effects, we performed microinjection of melatonin into various brain regions of the Japanese quail. On the basis of the injection site the effects of melatonin were dissociated into four groups: decrease in only body temperature, decrease in only locomotor activity, decrease in both body temperature and locomotor activity, and a change in neither. The decrease in only body temperature was observed when melatonin was injected into areas of the diencephalon including the thalamus and hypothalamus, and the decrease in only locomotor activity was observed when melatonin was injected close to the nuclei septalis medialis and septalis lateralis. These results suggest that melatonin-induced decreases in body temperature and locomotor activity occur by melatonin acting at discrete sites in the brain.",
keywords = "Body temperature, Circadian rhythm, Japanese quail, Locomotor activity, Melatonin",
author = "Keiko Nakahara and Takanori Kawano and Kunio Shiota and Noboru Murakami",
year = "2003",
month = "7",
day = "17",
doi = "10.1016/S0304-3940(03)00514-7",
language = "English",
volume = "345",
pages = "117--120",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Effects of microinjection of melatonin into various brain regions of Japanese quail on locomotor activity and body temperature

AU - Nakahara, Keiko

AU - Kawano, Takanori

AU - Shiota, Kunio

AU - Murakami, Noboru

PY - 2003/7/17

Y1 - 2003/7/17

N2 - We previously reported that peripheral administration of melatonin resulted in simultaneous decreases in locomotor activity and body temperature in the Japanese quail. To examine the site of these melatonin-induced effects, we performed microinjection of melatonin into various brain regions of the Japanese quail. On the basis of the injection site the effects of melatonin were dissociated into four groups: decrease in only body temperature, decrease in only locomotor activity, decrease in both body temperature and locomotor activity, and a change in neither. The decrease in only body temperature was observed when melatonin was injected into areas of the diencephalon including the thalamus and hypothalamus, and the decrease in only locomotor activity was observed when melatonin was injected close to the nuclei septalis medialis and septalis lateralis. These results suggest that melatonin-induced decreases in body temperature and locomotor activity occur by melatonin acting at discrete sites in the brain.

AB - We previously reported that peripheral administration of melatonin resulted in simultaneous decreases in locomotor activity and body temperature in the Japanese quail. To examine the site of these melatonin-induced effects, we performed microinjection of melatonin into various brain regions of the Japanese quail. On the basis of the injection site the effects of melatonin were dissociated into four groups: decrease in only body temperature, decrease in only locomotor activity, decrease in both body temperature and locomotor activity, and a change in neither. The decrease in only body temperature was observed when melatonin was injected into areas of the diencephalon including the thalamus and hypothalamus, and the decrease in only locomotor activity was observed when melatonin was injected close to the nuclei septalis medialis and septalis lateralis. These results suggest that melatonin-induced decreases in body temperature and locomotor activity occur by melatonin acting at discrete sites in the brain.

KW - Body temperature

KW - Circadian rhythm

KW - Japanese quail

KW - Locomotor activity

KW - Melatonin

UR - http://www.scopus.com/inward/record.url?scp=0037704309&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037704309&partnerID=8YFLogxK

U2 - 10.1016/S0304-3940(03)00514-7

DO - 10.1016/S0304-3940(03)00514-7

M3 - Article

VL - 345

SP - 117

EP - 120

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 2

ER -