Efficient route to RIKEN click probes for glycoconjugation

Kayo Nakamura, Kazuki Tsubokura, Almira Kurbangalieva, Yoichi Nakao, Takefumi Murase, Taiji Shimoda, Katsunori Tanaka

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A convenient route to RIKEN click probes for glycoconjugation to the amino groups of lysines was established. N-Glycoclusters prepared with human serum albumin by the new method showed the same cell interaction profiles as those synthesized previously. The new route has thus significantly expanding the applicability to glycoconjugation and drug delivery systems.

Original languageEnglish
Pages (from-to)127-138
Number of pages12
JournalJournal of Carbohydrate Chemistry
Volume38
Issue number2
DOIs
Publication statusPublished - 2019 Feb 12

Keywords

  • Albumin
  • RIKEN click probe
  • drug delivery system
  • glycocluster
  • glycoconjugation

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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