Electrochemical detection of viable bacteria in urine and antibiotic selection

Noriyuki Nakamura, Akinori Shigematsu, Tadashi Matsunaga*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


An electrode system consisting of a basal-plane pyrolytic graphite (BPG) electrode and a porous nitrocellulose membrane filter to trap bacteria was used for the detection of bacteria in urine. The peak current of a cyclic voltammogram increased with increasing initial cell concentration of Escherichia coli in urine. Urine containing from 5 × 102 to 5 × 105 cells ml-1 was measured with this system. The susceptibility of bacteria to various antibiotics was also determined from the peak current. The minimum inhibitory concentration values obtained by the electrochemical method were in good agreement with those obtained by the conventional method.

Original languageEnglish
Pages (from-to)575-580
Number of pages6
JournalBiosensors and Bioelectronics
Issue number7
Publication statusPublished - 1991
Externally publishedYes


  • antibiotics
  • cyclic voltammetry
  • electrochemical detection
  • urine

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Electrochemistry


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