Enantioselective intramolecular [2+2+2] cycloaddition of triynes for the synthesis of atropisomeric chiral ortho-diarylbenzene derivatives

Takanori Shibata, Kyoji Tsuchikama, Maiko Otsuka

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

An iridium-chiral diphosphine complex was used to catalyze an enantioselective [2+2+2] cycloaddition of oxygen- and nitrogen-bridged triynes with ortho-substituted aryl groups on their termini. ortho-Diarylbenzenes with atropisomeric chiralities were obtained in high yield and enantiomeric excess.

Original languageEnglish
Pages (from-to)614-619
Number of pages6
JournalTetrahedron Asymmetry
Volume17
Issue number4
DOIs
Publication statusPublished - 2006 Feb 20

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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