Enantioselective nucleophilic substitution of a 6,6-bicyclic dienyl acetate by palladium-chiral phosphine catalyst

Isao Shimizu, Yoshiyuki Matsumoto, Masahiro Nishikawa, Tamotsu Kawahara, Akiharu Satake, Akio Yamamoto

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The enantioselective nucleophilic substitution of (±)-2β-acetoxy-4aβ-methyl-2,3,4,4a,5,6-hexahydronaphthalene with dimethyl malonate anion was performed in the presence of palladium-chiral ligand catalysts to give optically active 2-di(methoxycarbonyl)methyl-4a-methyl-2,3,4,4a,5,6-hexahydronaphthalenes.

Original languageEnglish
Pages (from-to)983-984
Number of pages2
JournalChemistry Letters
Issue number10
Publication statusPublished - 1998

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phosphine
Palladium
Anions
Acetates
Substitution reactions
Ligands
Catalysts
methyl malonate

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Shimizu, I., Matsumoto, Y., Nishikawa, M., Kawahara, T., Satake, A., & Yamamoto, A. (1998). Enantioselective nucleophilic substitution of a 6,6-bicyclic dienyl acetate by palladium-chiral phosphine catalyst. Chemistry Letters, (10), 983-984.

Enantioselective nucleophilic substitution of a 6,6-bicyclic dienyl acetate by palladium-chiral phosphine catalyst. / Shimizu, Isao; Matsumoto, Yoshiyuki; Nishikawa, Masahiro; Kawahara, Tamotsu; Satake, Akiharu; Yamamoto, Akio.

In: Chemistry Letters, No. 10, 1998, p. 983-984.

Research output: Contribution to journalArticle

Shimizu, I, Matsumoto, Y, Nishikawa, M, Kawahara, T, Satake, A & Yamamoto, A 1998, 'Enantioselective nucleophilic substitution of a 6,6-bicyclic dienyl acetate by palladium-chiral phosphine catalyst', Chemistry Letters, no. 10, pp. 983-984.
Shimizu I, Matsumoto Y, Nishikawa M, Kawahara T, Satake A, Yamamoto A. Enantioselective nucleophilic substitution of a 6,6-bicyclic dienyl acetate by palladium-chiral phosphine catalyst. Chemistry Letters. 1998;(10):983-984.
Shimizu, Isao ; Matsumoto, Yoshiyuki ; Nishikawa, Masahiro ; Kawahara, Tamotsu ; Satake, Akiharu ; Yamamoto, Akio. / Enantioselective nucleophilic substitution of a 6,6-bicyclic dienyl acetate by palladium-chiral phosphine catalyst. In: Chemistry Letters. 1998 ; No. 10. pp. 983-984.
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