Enantioselective potential response of a human serum albumin-modified ITO electrode for tryptophan

Mariko Matsunaga, Tsubasa Ueno, Takuya Nakanishi, Tetsuya Osaka

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The present study aims at extending the possibility of utilizing bulky molecules such as proteins for fabricating electrochemical chiral sensors using an indium tin oxide (ITO) electrode. Enantioselective potential response of the human serum albumin (HSA)-modified ITO electrode was observed for tryptophan (Trp) when HSA was immobilized on an ITO electrode surface modified with disuccinimidyl suberate (DSS). In this sensing system, the enantioselective interaction between HSA and Trp is detected through the chemically reactive DSS group immobilized on the ITO electrode.

Original languageEnglish
Pages (from-to)1844-1846
Number of pages3
JournalElectrochemistry Communications
Volume10
Issue number12
DOIs
Publication statusPublished - 2008 Dec 1

Keywords

  • Asymmetric synthesis
  • Chiral sensor
  • Enantioselective
  • Field effect transistor
  • Indium tin oxide
  • Protein

ASJC Scopus subject areas

  • Electrochemistry

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