Enantioselective total synthesis of (-)-erinacine B

Hideaki Watanabe; Masashi Takano; Akinori Umino; Toshiya Ito; Hiroyuki Ishikawa; Masahisa Nakada

doi:10.1021/ol0628816

Enantioselective total synthesis of (-)-erinacine B

Hideaki Watanabe, Masashi Takano, Akinori Umino, Toshiya Ito, Hiroyuki Ishikawa, Masahisa Nakada^*

^*Corresponding author for this work

School of Advanced Science and Engineering

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

(Chemical Equation Presented) The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric catalysis developed by us and highly stereoselective construction of all stereogenic centers in the aglycon.

Original language	English
Pages (from-to)	359-362
Number of pages	4
Journal	Organic Letters
Volume	9
Issue number	2
DOIs	https://doi.org/10.1021/ol0628816
Publication status	Published - 2007 Jan 18

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.1021/ol0628816

Cite this

@article{9fca2043de15439eba52de34d2e02946,

title = "Enantioselective total synthesis of (-)-erinacine B",

abstract = "(Chemical Equation Presented) The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric catalysis developed by us and highly stereoselective construction of all stereogenic centers in the aglycon.",

author = "Hideaki Watanabe and Masashi Takano and Akinori Umino and Toshiya Ito and Hiroyuki Ishikawa and Masahisa Nakada",

year = "2007",

month = jan,

day = "18",

doi = "10.1021/ol0628816",

language = "English",

volume = "9",

pages = "359--362",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "2",

}

TY - JOUR

T1 - Enantioselective total synthesis of (-)-erinacine B

AU - Watanabe, Hideaki

AU - Takano, Masashi

AU - Umino, Akinori

AU - Ito, Toshiya

AU - Ishikawa, Hiroyuki

AU - Nakada, Masahisa

PY - 2007/1/18

Y1 - 2007/1/18

N2 - (Chemical Equation Presented) The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric catalysis developed by us and highly stereoselective construction of all stereogenic centers in the aglycon.

AB - (Chemical Equation Presented) The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric catalysis developed by us and highly stereoselective construction of all stereogenic centers in the aglycon.

UR - http://www.scopus.com/inward/record.url?scp=33846626841&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846626841&partnerID=8YFLogxK

U2 - 10.1021/ol0628816

DO - 10.1021/ol0628816

M3 - Article

C2 - 17217304

AN - SCOPUS:33846626841

SN - 1523-7060

VL - 9

SP - 359

EP - 362

JO - Organic Letters

JF - Organic Letters

IS - 2

ER -

Enantioselective total synthesis of (-)-erinacine B

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this