(Chemical Equation Presented) The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric catalysis developed by us and highly stereoselective construction of all stereogenic centers in the aglycon.
|Number of pages||4|
|Publication status||Published - 2007 Jan 18|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry