Endocrine and immune responses to resistance training in prostate cancer patients

D. A. Galvão, K. Nosaka, D. R. Taaffe, J. Peake, N. Spry, Katsuhiko Suzuki, K. Yamaya, M. R. McGuigan, L. J. Kristjanson, R. U. Newton

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.

Original languageEnglish
Pages (from-to)160-165
Number of pages6
JournalProstate Cancer and Prostatic Diseases
Volume11
Issue number2
DOIs
Publication statusPublished - 2008 Jun

Fingerprint

Resistance Training
Prostatic Neoplasms
Exercise
Dehydroepiandrosterone
Growth Hormone
Testosterone
Serum
Prostate-Specific Antigen
Leukocyte Count
Androgens
Interleukin-6
Tumor Necrosis Factor-alpha
Hormones
Muscles

ASJC Scopus subject areas

  • Oncology
  • Urology

Cite this

Endocrine and immune responses to resistance training in prostate cancer patients. / Galvão, D. A.; Nosaka, K.; Taaffe, D. R.; Peake, J.; Spry, N.; Suzuki, Katsuhiko; Yamaya, K.; McGuigan, M. R.; Kristjanson, L. J.; Newton, R. U.

In: Prostate Cancer and Prostatic Diseases, Vol. 11, No. 2, 06.2008, p. 160-165.

Research output: Contribution to journalArticle

Galvão, DA, Nosaka, K, Taaffe, DR, Peake, J, Spry, N, Suzuki, K, Yamaya, K, McGuigan, MR, Kristjanson, LJ & Newton, RU 2008, 'Endocrine and immune responses to resistance training in prostate cancer patients', Prostate Cancer and Prostatic Diseases, vol. 11, no. 2, pp. 160-165. https://doi.org/10.1038/sj.pcan.4500991
Galvão, D. A. ; Nosaka, K. ; Taaffe, D. R. ; Peake, J. ; Spry, N. ; Suzuki, Katsuhiko ; Yamaya, K. ; McGuigan, M. R. ; Kristjanson, L. J. ; Newton, R. U. / Endocrine and immune responses to resistance training in prostate cancer patients. In: Prostate Cancer and Prostatic Diseases. 2008 ; Vol. 11, No. 2. pp. 160-165.
@article{7573b7201a4640a98ce99db278e8b613,
title = "Endocrine and immune responses to resistance training in prostate cancer patients",
abstract = "This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.",
author = "Galv{\~a}o, {D. A.} and K. Nosaka and Taaffe, {D. R.} and J. Peake and N. Spry and Katsuhiko Suzuki and K. Yamaya and McGuigan, {M. R.} and Kristjanson, {L. J.} and Newton, {R. U.}",
year = "2008",
month = "6",
doi = "10.1038/sj.pcan.4500991",
language = "English",
volume = "11",
pages = "160--165",
journal = "Prostate Cancer and Prostatic Diseases",
issn = "1365-7852",
publisher = "Nature Publishing Group",
number = "2",

}

TY - JOUR

T1 - Endocrine and immune responses to resistance training in prostate cancer patients

AU - Galvão, D. A.

AU - Nosaka, K.

AU - Taaffe, D. R.

AU - Peake, J.

AU - Spry, N.

AU - Suzuki, Katsuhiko

AU - Yamaya, K.

AU - McGuigan, M. R.

AU - Kristjanson, L. J.

AU - Newton, R. U.

PY - 2008/6

Y1 - 2008/6

N2 - This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.

AB - This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.

UR - http://www.scopus.com/inward/record.url?scp=43549116414&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43549116414&partnerID=8YFLogxK

U2 - 10.1038/sj.pcan.4500991

DO - 10.1038/sj.pcan.4500991

M3 - Article

VL - 11

SP - 160

EP - 165

JO - Prostate Cancer and Prostatic Diseases

JF - Prostate Cancer and Prostatic Diseases

SN - 1365-7852

IS - 2

ER -