Engineering diversity into dynamic combinatorial libraries by use of a small flexible building block

Stuart J. Rowan, Philip S. Lukeman, Dominic J. Reynolds, Jeremy K M Sanders

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Oligomerization of preorganized cinchona and xanthene building blocks to produce dynamic combinatorial libraries results in libraries with only a few components. Diversity is generated by the addition of semi-flexible ephedrine and cholate building blocks.

Original languageEnglish
Pages (from-to)1015-1018
Number of pages4
JournalNew Journal of Chemistry
Volume22
Issue number10
Publication statusPublished - 1998 Oct
Externally publishedYes

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Cinchona
Xanthenes
Cholates
Ephedrine
Oligomerization

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Rowan, S. J., Lukeman, P. S., Reynolds, D. J., & Sanders, J. K. M. (1998). Engineering diversity into dynamic combinatorial libraries by use of a small flexible building block. New Journal of Chemistry, 22(10), 1015-1018.

Engineering diversity into dynamic combinatorial libraries by use of a small flexible building block. / Rowan, Stuart J.; Lukeman, Philip S.; Reynolds, Dominic J.; Sanders, Jeremy K M.

In: New Journal of Chemistry, Vol. 22, No. 10, 10.1998, p. 1015-1018.

Research output: Contribution to journalArticle

Rowan, SJ, Lukeman, PS, Reynolds, DJ & Sanders, JKM 1998, 'Engineering diversity into dynamic combinatorial libraries by use of a small flexible building block', New Journal of Chemistry, vol. 22, no. 10, pp. 1015-1018.
Rowan, Stuart J. ; Lukeman, Philip S. ; Reynolds, Dominic J. ; Sanders, Jeremy K M. / Engineering diversity into dynamic combinatorial libraries by use of a small flexible building block. In: New Journal of Chemistry. 1998 ; Vol. 22, No. 10. pp. 1015-1018.
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