Engineering diversity into dynamic combinatorial libraries by use of a small flexible building block

Stuart J. Rowan, Philip S. Lukeman, Dominic J. Reynolds, Jeremy K M Sanders

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

Oligomerization of preorganized cinchona and xanthene building blocks to produce dynamic combinatorial libraries results in libraries with only a few components. Diversity is generated by the addition of semi-flexible ephedrine and cholate building blocks.

Original languageEnglish
Pages (from-to)1015-1018
Number of pages4
JournalNew Journal of Chemistry
Volume22
Issue number10
Publication statusPublished - 1998 Oct
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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