Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe

N. Hirai, S. Uchida, T. Maehara, Y. Okubo, H. Shimizu

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

We performed fast Fourier transformation power spectral analysis of the electrocorticogram in human medial temporal lobe during wakeful rest in six epileptic subjects. Compared with the electrocorticogram wave in the basal temporal lobe, which showed monotonic decline of spectral power across the frequency axis, the electrocorticogram wave in the parahippocampal gyms was enhanced (or did not decline) in the gamma frequency range (30-150 Hz) in all subjects. Although it has been suggested that electrical oscillations of the hippocampus have functional roles in higher brain functions, namely learning and memory, the knowledge of hippocampal oscillations is largely limited to animal studies. The present results demonstrate that fast frequency oscillation is also present in the human medial temporal lobe, which has been reported in animal hippocampi. They also demonstrate the importance of recording very fast field potentials in human electrocorticograms. This fast oscillation is likely to play important functional roles related to learning and memory, possibly to induce long-term potentiation in the human medial temporal lobe.

Original languageEnglish
Pages (from-to)1149-1155
Number of pages7
JournalNeuroscience
Volume90
Issue number4
DOIs
Publication statusPublished - 1999 Jun
Externally publishedYes

Fingerprint

Temporal Lobe
Hippocampus
Learning
Long-Term Potentiation
Brain
Power (Psychology)

Keywords

  • Electrocorticogram
  • Gamma oscillation
  • Hippocampus
  • Human medial temporal lobe
  • Parahippocampal gyms
  • Spectral analysis

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Hirai, N., Uchida, S., Maehara, T., Okubo, Y., & Shimizu, H. (1999). Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe. Neuroscience, 90(4), 1149-1155. https://doi.org/10.1016/S0306-4522(98)00513-2

Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe. / Hirai, N.; Uchida, S.; Maehara, T.; Okubo, Y.; Shimizu, H.

In: Neuroscience, Vol. 90, No. 4, 06.1999, p. 1149-1155.

Research output: Contribution to journalArticle

Hirai, N, Uchida, S, Maehara, T, Okubo, Y & Shimizu, H 1999, 'Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe', Neuroscience, vol. 90, no. 4, pp. 1149-1155. https://doi.org/10.1016/S0306-4522(98)00513-2
Hirai, N. ; Uchida, S. ; Maehara, T. ; Okubo, Y. ; Shimizu, H. / Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe. In: Neuroscience. 1999 ; Vol. 90, No. 4. pp. 1149-1155.
@article{a066e4ad87464f8bb9677ab1de8c4be2,
title = "Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe",
abstract = "We performed fast Fourier transformation power spectral analysis of the electrocorticogram in human medial temporal lobe during wakeful rest in six epileptic subjects. Compared with the electrocorticogram wave in the basal temporal lobe, which showed monotonic decline of spectral power across the frequency axis, the electrocorticogram wave in the parahippocampal gyms was enhanced (or did not decline) in the gamma frequency range (30-150 Hz) in all subjects. Although it has been suggested that electrical oscillations of the hippocampus have functional roles in higher brain functions, namely learning and memory, the knowledge of hippocampal oscillations is largely limited to animal studies. The present results demonstrate that fast frequency oscillation is also present in the human medial temporal lobe, which has been reported in animal hippocampi. They also demonstrate the importance of recording very fast field potentials in human electrocorticograms. This fast oscillation is likely to play important functional roles related to learning and memory, possibly to induce long-term potentiation in the human medial temporal lobe.",
keywords = "Electrocorticogram, Gamma oscillation, Hippocampus, Human medial temporal lobe, Parahippocampal gyms, Spectral analysis",
author = "N. Hirai and S. Uchida and T. Maehara and Y. Okubo and H. Shimizu",
year = "1999",
month = "6",
doi = "10.1016/S0306-4522(98)00513-2",
language = "English",
volume = "90",
pages = "1149--1155",
journal = "Neuroscience",
issn = "0306-4522",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe

AU - Hirai, N.

AU - Uchida, S.

AU - Maehara, T.

AU - Okubo, Y.

AU - Shimizu, H.

PY - 1999/6

Y1 - 1999/6

N2 - We performed fast Fourier transformation power spectral analysis of the electrocorticogram in human medial temporal lobe during wakeful rest in six epileptic subjects. Compared with the electrocorticogram wave in the basal temporal lobe, which showed monotonic decline of spectral power across the frequency axis, the electrocorticogram wave in the parahippocampal gyms was enhanced (or did not decline) in the gamma frequency range (30-150 Hz) in all subjects. Although it has been suggested that electrical oscillations of the hippocampus have functional roles in higher brain functions, namely learning and memory, the knowledge of hippocampal oscillations is largely limited to animal studies. The present results demonstrate that fast frequency oscillation is also present in the human medial temporal lobe, which has been reported in animal hippocampi. They also demonstrate the importance of recording very fast field potentials in human electrocorticograms. This fast oscillation is likely to play important functional roles related to learning and memory, possibly to induce long-term potentiation in the human medial temporal lobe.

AB - We performed fast Fourier transformation power spectral analysis of the electrocorticogram in human medial temporal lobe during wakeful rest in six epileptic subjects. Compared with the electrocorticogram wave in the basal temporal lobe, which showed monotonic decline of spectral power across the frequency axis, the electrocorticogram wave in the parahippocampal gyms was enhanced (or did not decline) in the gamma frequency range (30-150 Hz) in all subjects. Although it has been suggested that electrical oscillations of the hippocampus have functional roles in higher brain functions, namely learning and memory, the knowledge of hippocampal oscillations is largely limited to animal studies. The present results demonstrate that fast frequency oscillation is also present in the human medial temporal lobe, which has been reported in animal hippocampi. They also demonstrate the importance of recording very fast field potentials in human electrocorticograms. This fast oscillation is likely to play important functional roles related to learning and memory, possibly to induce long-term potentiation in the human medial temporal lobe.

KW - Electrocorticogram

KW - Gamma oscillation

KW - Hippocampus

KW - Human medial temporal lobe

KW - Parahippocampal gyms

KW - Spectral analysis

UR - http://www.scopus.com/inward/record.url?scp=0032954378&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032954378&partnerID=8YFLogxK

U2 - 10.1016/S0306-4522(98)00513-2

DO - 10.1016/S0306-4522(98)00513-2

M3 - Article

C2 - 10338285

AN - SCOPUS:0032954378

VL - 90

SP - 1149

EP - 1155

JO - Neuroscience

JF - Neuroscience

SN - 0306-4522

IS - 4

ER -