Enhancement of an inhibitory input to the feeding central pattern generator in Lymnaea stagnalis during conditioned taste-aversion learning

Satoshi Kojima, Hiroshi Nanakamura, Shin Nagayama, Yutaka Fujito, Etsuro Ito

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

To study the neuronal mechanism of a conditioned taste-aversion (CTA) learning in the pond snail Lymnaea stagnalis, we examined the synaptic connection between the neuron 1 medial (N1M) cell and the cerebral giant cell (CGC), the former is an interneuron in central pattern generator for the feeding response and the latter is a regulatory neuron to the central pattern generator. Inhibitory postsynaptic potential (IPSP) which was evoked in the N1M cell by activation of the CGC was larger and lasted longer in the conditioned animal than that in the control animal. The electrical properties of the cell body of CGC and the responses of the CGC to the chemosensory inputs were not changed during the CTA learning. These results, together with the previous report indicating the existence of excitatory projection from the N1M cell to the feeding motoneuron, suggest that enhanced IPSP in the N1M cell may underlie the suppression of feeding responses in the Lymnaea CTA learning.

Original languageEnglish
Pages (from-to)179-182
Number of pages4
JournalNeuroscience Letters
Volume230
Issue number3
DOIs
Publication statusPublished - 1997 Jul 25
Externally publishedYes

Fingerprint

Central Pattern Generators
Lymnaea
Feeding Behavior
Giant Cells
Learning
Neurons
Inhibitory Postsynaptic Potentials
Snails
Motor Neurons
Interneurons

Keywords

  • Central pattern generator
  • Conditioned taste aversion
  • Feeding
  • Inhibitory postsynaptic potential
  • Lymnaea
  • Withdrawal

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Enhancement of an inhibitory input to the feeding central pattern generator in Lymnaea stagnalis during conditioned taste-aversion learning. / Kojima, Satoshi; Nanakamura, Hiroshi; Nagayama, Shin; Fujito, Yutaka; Ito, Etsuro.

In: Neuroscience Letters, Vol. 230, No. 3, 25.07.1997, p. 179-182.

Research output: Contribution to journalArticle

Kojima, Satoshi ; Nanakamura, Hiroshi ; Nagayama, Shin ; Fujito, Yutaka ; Ito, Etsuro. / Enhancement of an inhibitory input to the feeding central pattern generator in Lymnaea stagnalis during conditioned taste-aversion learning. In: Neuroscience Letters. 1997 ; Vol. 230, No. 3. pp. 179-182.
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