There are two approaches to the discovery of enzyme mimics, that is identifying molecules that are able to bind substrate(s) and then catalyse reactions. The first approach, often inspired by enzymes themselves, utilises chemical knowledge and experience to design the catalyst. The other approach is to create a library and select the best host of a transition state analogue of the required reaction.
|Number of pages||8|
|Journal||Current Opinion in Chemical Biology|
|Publication status||Published - 1997 Dec|
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