Esterification of Eschericia coli tRNAs with D-histidine and D-lysine by aminoacyl-tRNA synthetases

Toshimitsu Takayama, Tetsuhiro Ogawa, Makoto Hidaka, Yoshihiro Shimizu, Takuya Ueda, Haruhiko Masaki

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

It is generally believed that only L-amino acids are acceptable in protein synthesis, though some D-amino acids, including D-tyrosine, D-aspartate, and D-tryptophan are known to be bound enzymatically to tRNAs. In this report, we newly show that D-histidine and D-lysine are also able to be the substrates of respective Escherichia coli aminoacyl-tRNA synthetases.

Original languageEnglish
Pages (from-to)1040-1041
Number of pages2
JournalBioscience, Biotechnology and Biochemistry
Volume69
Issue number5
DOIs
Publication statusPublished - 2005 May 1
Externally publishedYes

Fingerprint

Amino Acyl-tRNA Synthetases
Esterification
Transfer RNA
Histidine
Lysine
D-Aspartic Acid
Amino Acids
Tryptophan
Escherichia coli
Tyrosine
Substrates
Proteins

Keywords

  • Aminoacyl-tRNA synthetase
  • D-amino acids

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biotechnology
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Esterification of Eschericia coli tRNAs with D-histidine and D-lysine by aminoacyl-tRNA synthetases. / Takayama, Toshimitsu; Ogawa, Tetsuhiro; Hidaka, Makoto; Shimizu, Yoshihiro; Ueda, Takuya; Masaki, Haruhiko.

In: Bioscience, Biotechnology and Biochemistry, Vol. 69, No. 5, 01.05.2005, p. 1040-1041.

Research output: Contribution to journalArticle

Takayama, Toshimitsu ; Ogawa, Tetsuhiro ; Hidaka, Makoto ; Shimizu, Yoshihiro ; Ueda, Takuya ; Masaki, Haruhiko. / Esterification of Eschericia coli tRNAs with D-histidine and D-lysine by aminoacyl-tRNA synthetases. In: Bioscience, Biotechnology and Biochemistry. 2005 ; Vol. 69, No. 5. pp. 1040-1041.
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