Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption

Ayano Kitamura, Marina Komatsu, Yoshimichi Ohki, Maya Mizuno, Miki Hirabayashi, Hiroaki Kojima

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2 Citations (Scopus)

    Abstract

    A new research trend that regards deoxyribonucleic acid (DNA) as a new dielectric polymeric material has been emerging in recent years. Especially for such application purposes, a simple easy-to-use method for determining the higher-order structure of synthetic DNA is desirable. From this viewpoint, we demonstrated in this research that far-infrared absorption spectroscopy can be a tool to determine the DNA higher-order structure and we calculated experimentally the integrated molar absorption coefficients per nucleotide with thymine at various frequencies. Therefore, using these coefficients, the number of thymine base on a single stranded DNA can be estimated by far-infrared spectroscopy.

    Original languageEnglish
    Title of host publicationAnnual Report - Conference on Electrical Insulation and Dielectric Phenomena, CEIDP
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    Pages617-620
    Number of pages4
    Volume2015-December
    ISBN (Print)9781467374972
    DOIs
    Publication statusPublished - 2015 Dec 9
    EventIEEE Conference on Electrical Insulation and Dielectric Phenomena, CEIDP 2015 - Ann Arbor, United States
    Duration: 2015 Oct 182015 Oct 21

    Other

    OtherIEEE Conference on Electrical Insulation and Dielectric Phenomena, CEIDP 2015
    CountryUnited States
    CityAnn Arbor
    Period15/10/1815/10/21

    Keywords

    • deoxyribonucleic acid
    • integrated molar absorbance coefficient
    • nucleotide
    • terahertz wave
    • thymine

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Electrical and Electronic Engineering

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  • Cite this

    Kitamura, A., Komatsu, M., Ohki, Y., Mizuno, M., Hirabayashi, M., & Kojima, H. (2015). Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption. In Annual Report - Conference on Electrical Insulation and Dielectric Phenomena, CEIDP (Vol. 2015-December, pp. 617-620). [7351989] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CEIDP.2015.7351989