Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads

Tohru Yoshioka, Hiroko Inoue, Takeshi Kasama, Yousuke Seyama, Shigeru Nakashima, Yoshinori Nozawa, Yoshiki Hotta

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We have found that arachidonic (20 : 4) acid is indetectable in phosphatidylinositol and diacylglycerol extracted from Drosophila heads. After careful examinations of the lipid extraction processes and fatty acid detection system (gas-liquid chromatography), we excluded the possibility of the oxidation of polyunsaturated fatty acids or of having overlooked a trace amount of the fatty acid. The precursors of arachidonic, dihomo γ-linolenic (20 : 3), and γ-linolenic (18 : 3) acid, were also indetectable in these lipids. On the basis of these results, it appears that the arachidonic acid cascade is essentially absent in Drosophila head, including the brain and compound eyes.Since arachidonic acid is considered to be a key molecule in phosphatidylinositol turnover in the brain, it is of interest that Drosophila brain and eyes do not require arachidonic acid for their functions.

Original languageEnglish
Pages (from-to)657-662
Number of pages6
JournalJournal of Biochemistry
Volume98
Issue number3
Publication statusPublished - 1985 Sep
Externally publishedYes

Fingerprint

Drosophilidae
Fatty Acids
Phosphatidylinositols
Arachidonic Acid
Drosophila
Brain
Head
Lipids
Acids
Fatty acids
Diglycerides
Liquid chromatography
Unsaturated Fatty Acids
Chromatography
Oxidation
Precursor
Gas chromatography
Gas Chromatography
Cascade
Polyunsaturated fatty acids

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Molecular Biology
  • Biochemistry

Cite this

Yoshioka, T., Inoue, H., Kasama, T., Seyama, Y., Nakashima, S., Nozawa, Y., & Hotta, Y. (1985). Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads. Journal of Biochemistry, 98(3), 657-662.

Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads. / Yoshioka, Tohru; Inoue, Hiroko; Kasama, Takeshi; Seyama, Yousuke; Nakashima, Shigeru; Nozawa, Yoshinori; Hotta, Yoshiki.

In: Journal of Biochemistry, Vol. 98, No. 3, 09.1985, p. 657-662.

Research output: Contribution to journalArticle

Yoshioka, T, Inoue, H, Kasama, T, Seyama, Y, Nakashima, S, Nozawa, Y & Hotta, Y 1985, 'Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads', Journal of Biochemistry, vol. 98, no. 3, pp. 657-662.
Yoshioka T, Inoue H, Kasama T, Seyama Y, Nakashima S, Nozawa Y et al. Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads. Journal of Biochemistry. 1985 Sep;98(3):657-662.
Yoshioka, Tohru ; Inoue, Hiroko ; Kasama, Takeshi ; Seyama, Yousuke ; Nakashima, Shigeru ; Nozawa, Yoshinori ; Hotta, Yoshiki. / Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads. In: Journal of Biochemistry. 1985 ; Vol. 98, No. 3. pp. 657-662.
@article{af8991922c0e4ca29513bbbb8caa2005,
title = "Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads",
abstract = "We have found that arachidonic (20 : 4) acid is indetectable in phosphatidylinositol and diacylglycerol extracted from Drosophila heads. After careful examinations of the lipid extraction processes and fatty acid detection system (gas-liquid chromatography), we excluded the possibility of the oxidation of polyunsaturated fatty acids or of having overlooked a trace amount of the fatty acid. The precursors of arachidonic, dihomo γ-linolenic (20 : 3), and γ-linolenic (18 : 3) acid, were also indetectable in these lipids. On the basis of these results, it appears that the arachidonic acid cascade is essentially absent in Drosophila head, including the brain and compound eyes.Since arachidonic acid is considered to be a key molecule in phosphatidylinositol turnover in the brain, it is of interest that Drosophila brain and eyes do not require arachidonic acid for their functions.",
author = "Tohru Yoshioka and Hiroko Inoue and Takeshi Kasama and Yousuke Seyama and Shigeru Nakashima and Yoshinori Nozawa and Yoshiki Hotta",
year = "1985",
month = "9",
language = "English",
volume = "98",
pages = "657--662",
journal = "Journal of Biochemistry",
issn = "0021-924X",
publisher = "Oxford University Press",
number = "3",

}

TY - JOUR

T1 - Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads

AU - Yoshioka, Tohru

AU - Inoue, Hiroko

AU - Kasama, Takeshi

AU - Seyama, Yousuke

AU - Nakashima, Shigeru

AU - Nozawa, Yoshinori

AU - Hotta, Yoshiki

PY - 1985/9

Y1 - 1985/9

N2 - We have found that arachidonic (20 : 4) acid is indetectable in phosphatidylinositol and diacylglycerol extracted from Drosophila heads. After careful examinations of the lipid extraction processes and fatty acid detection system (gas-liquid chromatography), we excluded the possibility of the oxidation of polyunsaturated fatty acids or of having overlooked a trace amount of the fatty acid. The precursors of arachidonic, dihomo γ-linolenic (20 : 3), and γ-linolenic (18 : 3) acid, were also indetectable in these lipids. On the basis of these results, it appears that the arachidonic acid cascade is essentially absent in Drosophila head, including the brain and compound eyes.Since arachidonic acid is considered to be a key molecule in phosphatidylinositol turnover in the brain, it is of interest that Drosophila brain and eyes do not require arachidonic acid for their functions.

AB - We have found that arachidonic (20 : 4) acid is indetectable in phosphatidylinositol and diacylglycerol extracted from Drosophila heads. After careful examinations of the lipid extraction processes and fatty acid detection system (gas-liquid chromatography), we excluded the possibility of the oxidation of polyunsaturated fatty acids or of having overlooked a trace amount of the fatty acid. The precursors of arachidonic, dihomo γ-linolenic (20 : 3), and γ-linolenic (18 : 3) acid, were also indetectable in these lipids. On the basis of these results, it appears that the arachidonic acid cascade is essentially absent in Drosophila head, including the brain and compound eyes.Since arachidonic acid is considered to be a key molecule in phosphatidylinositol turnover in the brain, it is of interest that Drosophila brain and eyes do not require arachidonic acid for their functions.

UR - http://www.scopus.com/inward/record.url?scp=0022368495&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022368495&partnerID=8YFLogxK

M3 - Article

VL - 98

SP - 657

EP - 662

JO - Journal of Biochemistry

JF - Journal of Biochemistry

SN - 0021-924X

IS - 3

ER -