Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads

Tohru Yoshioka, Hiroko Inoue, Takeshi Kasama, Yousuke Seyama, Shigeru Nakashima, Yoshinori Nozawa, Yoshiki Hotta

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

We have found that arachidonic (20 : 4) acid is indetectable in phosphatidylinositol and diacylglycerol extracted from Drosophila heads. After careful examinations of the lipid extraction processes and fatty acid detection system (gas-liquid chromatography), we excluded the possibility of the oxidation of polyunsaturated fatty acids or of having overlooked a trace amount of the fatty acid. The precursors of arachidonic, dihomo γ-linolenic (20 : 3), and γ-linolenic (18 : 3) acid, were also indetectable in these lipids. On the basis of these results, it appears that the arachidonic acid cascade is essentially absent in Drosophila head, including the brain and compound eyes.Since arachidonic acid is considered to be a key molecule in phosphatidylinositol turnover in the brain, it is of interest that Drosophila brain and eyes do not require arachidonic acid for their functions.

Original languageEnglish
Pages (from-to)657-662
Number of pages6
JournalJournal of Biochemistry
Volume98
Issue number3
Publication statusPublished - 1985 Sep
Externally publishedYes

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Molecular Biology
  • Biochemistry

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    Yoshioka, T., Inoue, H., Kasama, T., Seyama, Y., Nakashima, S., Nozawa, Y., & Hotta, Y. (1985). Evidence that arachidonic acid is deficient in phosphatidylinositol of Drosophila heads. Journal of Biochemistry, 98(3), 657-662.