Exercise and hormesis: Shaping the dose-response curve

Zsolt Radak

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Physical inactivity is a major contributor to the development of lifestyle-related diseases, including cardiovascular diseases (Lee et al. 2013; Oppewal et al. 2013), certain tumors, type 2 diabetes (Kasuga et al. 2013), osteoporosis (Janssen 2012), and even neurodegenerative diseases (Radak et al. 2010; Janssen 2012). This could be partly because the development of the genome at the genesis of humans was associated with a physically active lifestyle. It has been suggested that Stone Age man used 4000 kcal for physical activity on a daily basis (Radak et al. 2013c). Adaptive changes on the DNA sequence are very slow. Therefore, it is not surprising that physical inactivity is a risk factor for a wide range of diseases.

Original languageEnglish
Title of host publicationHormesis in Health and Disease
PublisherCRC Press
Pages37-44
Number of pages8
ISBN (Electronic)9781482205466
ISBN (Print)9781482205459
DOIs
Publication statusPublished - 2014 Jan 1
Externally publishedYes

Fingerprint

Hormesis
Life Style
Exercise
Neurodegenerative Diseases
Neurodegenerative diseases
Type 2 Diabetes Mellitus
Osteoporosis
Cardiovascular Diseases
DNA sequences
Genome
Medical problems
Tumors
Genes
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Radak, Z. (2014). Exercise and hormesis: Shaping the dose-response curve. In Hormesis in Health and Disease (pp. 37-44). CRC Press. https://doi.org/10.1201/b17042

Exercise and hormesis : Shaping the dose-response curve. / Radak, Zsolt.

Hormesis in Health and Disease. CRC Press, 2014. p. 37-44.

Research output: Chapter in Book/Report/Conference proceedingChapter

Radak, Z 2014, Exercise and hormesis: Shaping the dose-response curve. in Hormesis in Health and Disease. CRC Press, pp. 37-44. https://doi.org/10.1201/b17042
Radak Z. Exercise and hormesis: Shaping the dose-response curve. In Hormesis in Health and Disease. CRC Press. 2014. p. 37-44 https://doi.org/10.1201/b17042
Radak, Zsolt. / Exercise and hormesis : Shaping the dose-response curve. Hormesis in Health and Disease. CRC Press, 2014. pp. 37-44
@inbook{dc7031d9838c47b8b24c7dd795c45683,
title = "Exercise and hormesis: Shaping the dose-response curve",
abstract = "Physical inactivity is a major contributor to the development of lifestyle-related diseases, including cardiovascular diseases (Lee et al. 2013; Oppewal et al. 2013), certain tumors, type 2 diabetes (Kasuga et al. 2013), osteoporosis (Janssen 2012), and even neurodegenerative diseases (Radak et al. 2010; Janssen 2012). This could be partly because the development of the genome at the genesis of humans was associated with a physically active lifestyle. It has been suggested that Stone Age man used 4000 kcal for physical activity on a daily basis (Radak et al. 2013c). Adaptive changes on the DNA sequence are very slow. Therefore, it is not surprising that physical inactivity is a risk factor for a wide range of diseases.",
author = "Zsolt Radak",
year = "2014",
month = "1",
day = "1",
doi = "10.1201/b17042",
language = "English",
isbn = "9781482205459",
pages = "37--44",
booktitle = "Hormesis in Health and Disease",
publisher = "CRC Press",

}

TY - CHAP

T1 - Exercise and hormesis

T2 - Shaping the dose-response curve

AU - Radak, Zsolt

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Physical inactivity is a major contributor to the development of lifestyle-related diseases, including cardiovascular diseases (Lee et al. 2013; Oppewal et al. 2013), certain tumors, type 2 diabetes (Kasuga et al. 2013), osteoporosis (Janssen 2012), and even neurodegenerative diseases (Radak et al. 2010; Janssen 2012). This could be partly because the development of the genome at the genesis of humans was associated with a physically active lifestyle. It has been suggested that Stone Age man used 4000 kcal for physical activity on a daily basis (Radak et al. 2013c). Adaptive changes on the DNA sequence are very slow. Therefore, it is not surprising that physical inactivity is a risk factor for a wide range of diseases.

AB - Physical inactivity is a major contributor to the development of lifestyle-related diseases, including cardiovascular diseases (Lee et al. 2013; Oppewal et al. 2013), certain tumors, type 2 diabetes (Kasuga et al. 2013), osteoporosis (Janssen 2012), and even neurodegenerative diseases (Radak et al. 2010; Janssen 2012). This could be partly because the development of the genome at the genesis of humans was associated with a physically active lifestyle. It has been suggested that Stone Age man used 4000 kcal for physical activity on a daily basis (Radak et al. 2013c). Adaptive changes on the DNA sequence are very slow. Therefore, it is not surprising that physical inactivity is a risk factor for a wide range of diseases.

UR - http://www.scopus.com/inward/record.url?scp=85054662473&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85054662473&partnerID=8YFLogxK

U2 - 10.1201/b17042

DO - 10.1201/b17042

M3 - Chapter

AN - SCOPUS:85054662473

SN - 9781482205459

SP - 37

EP - 44

BT - Hormesis in Health and Disease

PB - CRC Press

ER -