Fabrication of micro-gelatin fiber utilizing coacervation method

Takafumi Arai, Ryuichiro Tanaka, Katsuhisa Sakaguchi, Shinjiro Umezu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Biotechnology has drastically been advanced by the development of iPS and ES cells, which are representative forms induced pluripotent stem cells. In the micro/nano bio field, the development of cells and Taylor-made medicine for a potential treatment of incurable diseases has been a center of attention. The melting point of gelatin is between 25 and 33 °C, and the sol–gel transition occurs in low temperature. This makes the deformation of this useful biomaterial easy. The examples of gelatin fiber applications are suture threads, blood vessel prosthesis, cell-growth-based materials, filter materials, and many others. Because the cell size differs depending on the species and applications, it is essential to fabricate gelatin fibers of different diameters. In this paper, we have developed a fabrication method for gelatin fibers the coacervation method. We fabricated narrow gelatin fibers having a diameter over 10 μm.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalArtificial Life and Robotics
DOIs
Publication statusAccepted/In press - 2016 Dec 23

Fingerprint

Gelatin
Fabrication
Fibers
Blood vessel prostheses
Bioelectric potentials
Blood Vessel Prosthesis
Cell growth
Biotechnology
Induced Pluripotent Stem Cells
Stem cells
Biomaterials
Medicine
Melting point
Biocompatible Materials
Cell Size
Sutures
Freezing
Temperature
Growth

Keywords

  • Coacervation
  • Fiber
  • Gelatin
  • Oil coating

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Artificial Intelligence

Cite this

Fabrication of micro-gelatin fiber utilizing coacervation method. / Arai, Takafumi; Tanaka, Ryuichiro; Sakaguchi, Katsuhisa; Umezu, Shinjiro.

In: Artificial Life and Robotics, 23.12.2016, p. 1-6.

Research output: Contribution to journalArticle

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