Fabrication of post-hydrophilic treatment-free plastic biochip using polyurea film

Hidetoshi Shinohara, Yoshikazu Takahashi, Jun Mizuno, Shuichi Shoji

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A novel low-temperature bonding method was developed by using polyurea film as intermediate layers. A microchip with a microchannel having a highly hydrophilic surface was realized by pretreatment with vacuum ultraviolet light irradiation under an oxygen atmosphere (VUV/O3). The bonding temperature is low enough to use thermo-plastic channel plates such as PMMA (poly(methyl methacrylate)) with negligible deformation of the channel structure. The results of contact angle measurements indicate the highly hydrophilic surface of the microchannel was retained after the bonding process. There was no leakage or obstacles to smooth fluidic flow at the bonded interface. For actual micro-biochip fabrication with this method, the post-hydrophilic treatment after bonding process is unnecessary.

Original languageEnglish
Pages (from-to)187-191
Number of pages5
JournalSensors and Actuators, A: Physical
Volume154
Issue number2
DOIs
Publication statusPublished - 2009 Sep 24

Fingerprint

Biochips
plastics
Plastics
Fabrication
fabrication
Polymethyl Methacrylate
microchannels
Microchannels
fluidics
Fluidics
Angle measurement
Polymethyl methacrylates
polymethyl methacrylate
ultraviolet radiation
pretreatment
Contact angle
leakage
Irradiation
Vacuum
Oxygen

Keywords

  • Bonding
  • Hydrophilicity
  • Microchannel
  • Polyurea
  • Vacuum ultraviolet

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials
  • Metals and Alloys
  • Surfaces, Coatings and Films
  • Instrumentation

Cite this

Fabrication of post-hydrophilic treatment-free plastic biochip using polyurea film. / Shinohara, Hidetoshi; Takahashi, Yoshikazu; Mizuno, Jun; Shoji, Shuichi.

In: Sensors and Actuators, A: Physical, Vol. 154, No. 2, 24.09.2009, p. 187-191.

Research output: Contribution to journalArticle

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