Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex

Maiko Otsuka, Hiroya Yokoyama, Kohei Endo, Takanori Shibata

    Research output: Contribution to journalArticle

    14 Citations (Scopus)

    Abstract

    Catalytic SNAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl2] 2, AgOTf, and P(p-FC6H4)3. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.

    Original languageEnglish
    Pages (from-to)2601-2606
    Number of pages6
    JournalSynlett
    Issue number17
    DOIs
    Publication statusPublished - 2010

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    Keywords

    • amines
    • catalysis
    • fluoroarenes
    • ruthenium
    • SAr reaction

    ASJC Scopus subject areas

    • Organic Chemistry

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