Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex

Maiko Otsuka; Hiroya Yokoyama; Kohei Endo; Takanori Shibata

doi:10.1055/s-0030-1258774

Facile catalytic S_NAr reaction of nonactivated fluoroarenes with amines using η⁶-benzene ruthenium(II) complex

Maiko Otsuka, Hiroya Yokoyama, Kohei Endo, Takanori Shibata

School of Advanced Science and Engineering

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Catalytic S_NAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl₂] ₂, AgOTf, and P(p-FC₆H₄)₃. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.

Original language	English
Pages (from-to)	2601-2606
Number of pages	6
Journal	Synlett
Issue number	17
DOIs	https://doi.org/10.1055/s-0030-1258774
Publication status	Published - 2010 Oct 25

Keywords

SAr reaction
amines
catalysis
fluoroarenes
ruthenium

ASJC Scopus subject areas

Organic Chemistry

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abstract = "Catalytic SNAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl2] 2, AgOTf, and P(p-FC6H4)3. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.",

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AU - Endo, Kohei

AU - Shibata, Takanori

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AB - Catalytic SNAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl2] 2, AgOTf, and P(p-FC6H4)3. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.

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KW - catalysis

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KW - ruthenium

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