Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex

Maiko Otsuka, Hiroya Yokoyama, Kohei Endo, Takanori Shibata

    Research output: Contribution to journal › Article

    12 Citations (Scopus)

    Abstract

    Catalytic SNAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl2] 2, AgOTf, and P(p-FC6H4)3. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.

    Original languageEnglish
    Pages (from-to)2601-2606
    Number of pages6
    JournalSynlett
    Issue number17
    DOIs
    Publication statusPublished - 2010

    Fingerprint

    Ruthenium
    Benzene
    Amines
    Molecular sieves
    Catalysts
    Electrons

    Keywords

    • amines
    • catalysis
    • fluoroarenes
    • ruthenium
    • SAr reaction

    ASJC Scopus subject areas

    • Organic Chemistry

    Cite this

    Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex. / Otsuka, Maiko; Yokoyama, Hiroya; Endo, Kohei; Shibata, Takanori.

    In: Synlett, No. 17, 2010, p. 2601-2606.

    Research output: Contribution to journal › Article

    Otsuka, M, Yokoyama, H, Endo, K & Shibata, T 2010, 'Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex', Synlett, no. 17, pp. 2601-2606. https://doi.org/10.1055/s-0030-1258774
    Otsuka M, Yokoyama H, Endo K, Shibata T. Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex. Synlett. 2010;(17):2601-2606. https://doi.org/10.1055/s-0030-1258774
    Otsuka, Maiko ; Yokoyama, Hiroya ; Endo, Kohei ; Shibata, Takanori. / Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex. In: Synlett. 2010 ; No. 17. pp. 2601-2606.
    @article{5f3ed5c47acd4ad0b5a1a52a5c73689d,
    title = "Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex",
    abstract = "Catalytic SNAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl2] 2, AgOTf, and P(p-FC6H4)3. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.",
    keywords = "amines, catalysis, fluoroarenes, ruthenium, SAr reaction",
    author = "Maiko Otsuka and Hiroya Yokoyama and Kohei Endo and Takanori Shibata",
    year = "2010",
    doi = "10.1055/s-0030-1258774",
    language = "English",
    pages = "2601--2606",
    journal = "Synlett",
    issn = "0936-5214",
    publisher = "Georg Thieme Verlag",
    number = "17",

    }

    TY - JOUR

    T1 - Facile catalytic SNAr reaction of nonactivated fluoroarenes with amines using η6-benzene ruthenium(II) complex

    AU - Otsuka, Maiko

    AU - Yokoyama, Hiroya

    AU - Endo, Kohei

    AU - Shibata, Takanori

    PY - 2010

    Y1 - 2010

    N2 - Catalytic SNAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl2] 2, AgOTf, and P(p-FC6H4)3. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.

    AB - Catalytic SNAr reaction of fluoroarenes possessing no electron-withdrawing group(s) with cyclic amines was achieved using a readily accessible Ru catalyst, which was prepared from [Ru(benzene)Cl2] 2, AgOTf, and P(p-FC6H4)3. The coexistence of molecular sieves MS4A realized high conversion and various substituted aryl amines were obtained in good to high yields.

    KW - amines

    KW - catalysis

    KW - fluoroarenes

    KW - ruthenium

    KW - SAr reaction

    UR - http://www.scopus.com/inward/record.url?scp=77958029099&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=77958029099&partnerID=8YFLogxK

    U2 - 10.1055/s-0030-1258774

    DO - 10.1055/s-0030-1258774

    M3 - Article

    SP - 2601

    EP - 2606

    JO - Synlett

    JF - Synlett

    SN - 0936-5214

    IS - 17

    ER -

    Access to Document