Facile synthesis of (-)-serricornin by means of palladium-catalyzed hydrogenolysis of alkenyloxiranes

Isao Shimizu, Kaoruko Hayashi, Nobuyuki Ide, Masato Oshima

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Chiral synthesis of (-)-serricornin by using palladium-catalyzed stereoselective hydrogenolysis of the alkenyloxirane to the homoallylic alcohol with formic acid as a key step was carried out.

Original languageEnglish
Pages (from-to)2991-2998
Number of pages8
JournalTetrahedron
Volume47
Issue number18-19
DOIs
Publication statusPublished - 1991 May 6

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formic acid
Hydrogenolysis
Palladium
Alcohols
serricornin

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Facile synthesis of (-)-serricornin by means of palladium-catalyzed hydrogenolysis of alkenyloxiranes. / Shimizu, Isao; Hayashi, Kaoruko; Ide, Nobuyuki; Oshima, Masato.

In: Tetrahedron, Vol. 47, No. 18-19, 06.05.1991, p. 2991-2998.

Research output: Contribution to journalArticle

Shimizu, Isao ; Hayashi, Kaoruko ; Ide, Nobuyuki ; Oshima, Masato. / Facile synthesis of (-)-serricornin by means of palladium-catalyzed hydrogenolysis of alkenyloxiranes. In: Tetrahedron. 1991 ; Vol. 47, No. 18-19. pp. 2991-2998.
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