Abstract
Background: Pylorus-preserving gastrectomy (PPG) is sometimes performed as a function-preserving surgery for the treatment of early gastric cancer. The aim of this study was to use an integrated assessment scale for postgastrectomy syndrome to determine the appropriate indicators and optimal methods for PPG.Methods: The Postgastrectomy Syndrome Assessment Study (PGSAS) is a multicenter survey based on an integrated questionnaire (PGSAS-45) consisting of 45 items. Questionnaire responses were retrieved from a total of 2,520 patients, each of whom had undergone one of six different types of gastrectomy procedures; 313 responses from patients who had received PPG were analyzed here.Results: The size of the proximal gastric remnant (less than one-quarter, about one-third, or more than one-half of the original size) significantly influenced the change in body weight, the scores for dissatisfaction at the meal, and dissatisfaction for daily life subscale (P = 0.030, P = 0.005, P = 0.034, respectively). The nausea score in patients who underwent hand-sewn anastomosis was significantly lower than in those who underwent anastomosis with a linear stapler (P = 0.006). The scores for diarrhea subscale, increased passage of stools, and sense of foods sticking differed significantly depending on the length of the preserved pyloric cuff (P = 0.047, P = 0.021, P = 0.046, respectively).Conclusions: The results suggest that preservation of a sufficient proximal gastric remnant is recommended when utilizing PPG as function-preserving surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 397-406 |
| Number of pages | 10 |
| Journal | Gastric Cancer |
| Volume | 18 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2015 Apr 1 |
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Keywords
- Early gastric cancer
- Function-preserving surgery
- Postgastrectomy syndrome
- Pylorus-preserving gastrectomy
- Quality of life
ASJC Scopus subject areas
- Oncology
- Gastroenterology
- Cancer Research
Cite this
Factors that minimize postgastrectomy symptoms following pylorus-preserving gastrectomy : assessment using a newly developed scale (PGSAS-45). / Namikawa, Tsutomu; Hiki, Naoki; Kinami, Shinichi; Okabe, Hiroshi; Urushihara, Takashi; Kawahira, Hiroshi; Fukushima, Norimasa; Kodera, Yasuhiro; Yumiba, Takeyoshi; Oshio, Atsushi; Nakada, Koji.
In: Gastric Cancer, Vol. 18, No. 2, 01.04.2015, p. 397-406.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Factors that minimize postgastrectomy symptoms following pylorus-preserving gastrectomy
T2 - assessment using a newly developed scale (PGSAS-45)
AU - Namikawa, Tsutomu
AU - Hiki, Naoki
AU - Kinami, Shinichi
AU - Okabe, Hiroshi
AU - Urushihara, Takashi
AU - Kawahira, Hiroshi
AU - Fukushima, Norimasa
AU - Kodera, Yasuhiro
AU - Yumiba, Takeyoshi
AU - Oshio, Atsushi
AU - Nakada, Koji
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Background: Pylorus-preserving gastrectomy (PPG) is sometimes performed as a function-preserving surgery for the treatment of early gastric cancer. The aim of this study was to use an integrated assessment scale for postgastrectomy syndrome to determine the appropriate indicators and optimal methods for PPG.Methods: The Postgastrectomy Syndrome Assessment Study (PGSAS) is a multicenter survey based on an integrated questionnaire (PGSAS-45) consisting of 45 items. Questionnaire responses were retrieved from a total of 2,520 patients, each of whom had undergone one of six different types of gastrectomy procedures; 313 responses from patients who had received PPG were analyzed here.Results: The size of the proximal gastric remnant (less than one-quarter, about one-third, or more than one-half of the original size) significantly influenced the change in body weight, the scores for dissatisfaction at the meal, and dissatisfaction for daily life subscale (P = 0.030, P = 0.005, P = 0.034, respectively). The nausea score in patients who underwent hand-sewn anastomosis was significantly lower than in those who underwent anastomosis with a linear stapler (P = 0.006). The scores for diarrhea subscale, increased passage of stools, and sense of foods sticking differed significantly depending on the length of the preserved pyloric cuff (P = 0.047, P = 0.021, P = 0.046, respectively).Conclusions: The results suggest that preservation of a sufficient proximal gastric remnant is recommended when utilizing PPG as function-preserving surgery.
AB - Background: Pylorus-preserving gastrectomy (PPG) is sometimes performed as a function-preserving surgery for the treatment of early gastric cancer. The aim of this study was to use an integrated assessment scale for postgastrectomy syndrome to determine the appropriate indicators and optimal methods for PPG.Methods: The Postgastrectomy Syndrome Assessment Study (PGSAS) is a multicenter survey based on an integrated questionnaire (PGSAS-45) consisting of 45 items. Questionnaire responses were retrieved from a total of 2,520 patients, each of whom had undergone one of six different types of gastrectomy procedures; 313 responses from patients who had received PPG were analyzed here.Results: The size of the proximal gastric remnant (less than one-quarter, about one-third, or more than one-half of the original size) significantly influenced the change in body weight, the scores for dissatisfaction at the meal, and dissatisfaction for daily life subscale (P = 0.030, P = 0.005, P = 0.034, respectively). The nausea score in patients who underwent hand-sewn anastomosis was significantly lower than in those who underwent anastomosis with a linear stapler (P = 0.006). The scores for diarrhea subscale, increased passage of stools, and sense of foods sticking differed significantly depending on the length of the preserved pyloric cuff (P = 0.047, P = 0.021, P = 0.046, respectively).Conclusions: The results suggest that preservation of a sufficient proximal gastric remnant is recommended when utilizing PPG as function-preserving surgery.
KW - Early gastric cancer
KW - Function-preserving surgery
KW - Postgastrectomy syndrome
KW - Pylorus-preserving gastrectomy
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84925632329&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84925632329&partnerID=8YFLogxK
U2 - 10.1007/s10120-014-0366-y
DO - 10.1007/s10120-014-0366-y
M3 - Article
C2 - 24760336
AN - SCOPUS:84925632329
VL - 18
SP - 397
EP - 406
JO - Gastric Cancer
JF - Gastric Cancer
SN - 1436-3291
IS - 2
ER -