Flexible control of electrode pattern on cultivation chamber during cultivation of cells using nondestructive optical etching

Kensuke Kojima, Kazunori Takahashi, Tomoyuki Kaneko, Kenji Yasuda

Research output: Contribution to journalLetter

5 Citations (Scopus)

Abstract

We have developed a method for flexible changing the shape of the electrode layer on a cultivation chip by nondestructive optical etching with a focused 1064 nm infrared laser during cultivation of cells on it. When the etched width of the scratch on the electrode layer of cultivation chip reached 10 μm, the conductance decreased to 0 S. The method was then examined for the area-specific stimulation of cardiac myocytes cultivated on the chip, and was found to stimulated the cells in the area successfully. The result indicates the ability of flexible-area-specific electric stimulation to change the shape of an electrode during cultivation.

Original languageEnglish
JournalJapanese Journal of Applied Physics, Part 2: Letters
Volume42
Issue number8 A
Publication statusPublished - 2003 Aug 1
Externally publishedYes

Fingerprint

Etching
chambers
etching
Electrodes
electrodes
chips
cells
stimulation
muscle cells
Infrared lasers
infrared lasers

Keywords

  • Cardiac myocyte
  • Cell cultivation
  • Electric stimulation
  • Electrode pattern
  • Flexible change
  • Nondestructive optical etching

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

Cite this

Flexible control of electrode pattern on cultivation chamber during cultivation of cells using nondestructive optical etching. / Kojima, Kensuke; Takahashi, Kazunori; Kaneko, Tomoyuki; Yasuda, Kenji.

In: Japanese Journal of Applied Physics, Part 2: Letters, Vol. 42, No. 8 A, 01.08.2003.

Research output: Contribution to journalLetter

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AU - Kaneko, Tomoyuki

AU - Yasuda, Kenji

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N2 - We have developed a method for flexible changing the shape of the electrode layer on a cultivation chip by nondestructive optical etching with a focused 1064 nm infrared laser during cultivation of cells on it. When the etched width of the scratch on the electrode layer of cultivation chip reached 10 μm, the conductance decreased to 0 S. The method was then examined for the area-specific stimulation of cardiac myocytes cultivated on the chip, and was found to stimulated the cells in the area successfully. The result indicates the ability of flexible-area-specific electric stimulation to change the shape of an electrode during cultivation.

AB - We have developed a method for flexible changing the shape of the electrode layer on a cultivation chip by nondestructive optical etching with a focused 1064 nm infrared laser during cultivation of cells on it. When the etched width of the scratch on the electrode layer of cultivation chip reached 10 μm, the conductance decreased to 0 S. The method was then examined for the area-specific stimulation of cardiac myocytes cultivated on the chip, and was found to stimulated the cells in the area successfully. The result indicates the ability of flexible-area-specific electric stimulation to change the shape of an electrode during cultivation.

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KW - Electric stimulation

KW - Electrode pattern

KW - Flexible change

KW - Nondestructive optical etching

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