Fluid-structure interaction modeling of aneurysmal conditions with high and normal blood pressures

Ryo Torii, Marie Oshima, Toshio Kobayashi, Kiyoshi Takagi, Tayfun E. Tezduyar

Research output: Contribution to journalArticle

129 Citations (Scopus)

Abstract

Hemodynamic factors like the wall shear stress play an important role in cardiovascular diseases. To investigate the influence of hemodynamic factors in blood vessels, the authors have developed a numerical fluid-structure interaction (FSI) analysis technique. The objective is to use numerical simulation as an effective tool to predict phenomena in a living human body. We applied the technique to a patient-specific arterial model, and with that we showed the effect of wall deformation on the WSS distribution. In this paper, we compute the interaction between the blood flow and the arterial wall for a patient-specific cerebral aneurysm with various hemodynamic conditions, such as hypertension. We particularly focus on the effects of hypertensive blood pressure on the interaction and the WSS, because hypertension is reported to be a risk factor in rupture of aneurysms. We also aim to show the possibility of FSI computations with hemodynamic conditions representing those risk factors in cardiovascular disease. The simulations show that the transient behavior of the interaction under hypertensive blood pressure is significantly different from the interaction under normal blood pressure. The transient behavior of the blood-flow velocity, and the resulting WSS and the mechanical stress in the aneurysmal wall, are significantly affected by hypertension. The results imply that hypertension affects the growth of an aneurysm and the damage in arterial tissues.

Original languageEnglish
Pages (from-to)482-490
Number of pages9
JournalComputational Mechanics
Volume38
Issue number4-5
DOIs
Publication statusPublished - 2006 Sep
Externally publishedYes

Fingerprint

Fluid structure interaction
Blood pressure
Blood Pressure
Hemodynamics
Hypertension
Fluid
Interaction
Modeling
Aneurysm
Blood
Transient Behavior
Risk Factors
Blood Flow
Blood vessels
Cerebral Aneurysm
Flow velocity
Shear stress
Mechanical Stress
Wall Shear Stress
Blood Vessels

Keywords

  • Cardiovascular modeling
  • Fluid-structure interaction
  • Hypertension
  • Patient-specific computation

ASJC Scopus subject areas

  • Mechanics of Materials
  • Computational Mechanics
  • Applied Mathematics
  • Safety, Risk, Reliability and Quality

Cite this

Fluid-structure interaction modeling of aneurysmal conditions with high and normal blood pressures. / Torii, Ryo; Oshima, Marie; Kobayashi, Toshio; Takagi, Kiyoshi; Tezduyar, Tayfun E.

In: Computational Mechanics, Vol. 38, No. 4-5, 09.2006, p. 482-490.

Research output: Contribution to journalArticle

Torii, Ryo ; Oshima, Marie ; Kobayashi, Toshio ; Takagi, Kiyoshi ; Tezduyar, Tayfun E. / Fluid-structure interaction modeling of aneurysmal conditions with high and normal blood pressures. In: Computational Mechanics. 2006 ; Vol. 38, No. 4-5. pp. 482-490.
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