Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice

A reply to Fuller et al

Ralph E. Mistlberger, Ruud M. Buijs, Etienne Challet, Carolina Escobar, Glenn J. Landry, Andries Kalsbeek, Paul Pevet, Shigenobu Shibata

    Research output: Contribution to journalArticle

    9 Citations (Scopus)

    Abstract

    Evidence that circadian food-anticipatory activity and temperature rhythms are absent in Bmal1 knockout mice and rescued by restoration of Bmal1 expression selectively in the dorsomedial hypothalamus was published in 2008 by Fuller et al and critiqued in 2009 by Mistlberger et al. Fuller et al have responded to the critique with new information. Here we update our critique in the light of this new information. We also identify and correct factual and conceptual errors in the Fuller et al response. We conclude that the original results of Fuller et al remain inconclusive and fail to clarify the role of Bmal1 or the dorsomedial hypothalamus in the generation of food-entrainable rhythms in mice.

    Original languageEnglish
    Article number11
    JournalJournal of Circadian Rhythms
    Volume7
    DOIs
    Publication statusPublished - 2009 Aug 10

    Fingerprint

    Hypothalamus
    Food
    Knockout Mice
    Temperature

    ASJC Scopus subject areas

    • Physiology
    • Endocrine and Autonomic Systems

    Cite this

    Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice : A reply to Fuller et al. / Mistlberger, Ralph E.; Buijs, Ruud M.; Challet, Etienne; Escobar, Carolina; Landry, Glenn J.; Kalsbeek, Andries; Pevet, Paul; Shibata, Shigenobu.

    In: Journal of Circadian Rhythms, Vol. 7, 11, 10.08.2009.

    Research output: Contribution to journalArticle

    Mistlberger, RE, Buijs, RM, Challet, E, Escobar, C, Landry, GJ, Kalsbeek, A, Pevet, P & Shibata, S 2009, 'Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: A reply to Fuller et al', Journal of Circadian Rhythms, vol. 7, 11. https://doi.org/10.1186/1740-3391-7-11
    Mistlberger RE, Buijs RM, Challet E, Escobar C, Landry GJ, Kalsbeek A et al. Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: A reply to Fuller et al. Journal of Circadian Rhythms. 2009 Aug 10;7. 11. https://doi.org/10.1186/1740-3391-7-11
    Mistlberger, Ralph E. ; Buijs, Ruud M. ; Challet, Etienne ; Escobar, Carolina ; Landry, Glenn J. ; Kalsbeek, Andries ; Pevet, Paul ; Shibata, Shigenobu. / Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice : A reply to Fuller et al. In: Journal of Circadian Rhythms. 2009 ; Vol. 7.
    @article{69b5c5dfa1ba4ac8adf8d37df23fe0a5,
    title = "Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: A reply to Fuller et al",
    abstract = "Evidence that circadian food-anticipatory activity and temperature rhythms are absent in Bmal1 knockout mice and rescued by restoration of Bmal1 expression selectively in the dorsomedial hypothalamus was published in 2008 by Fuller et al and critiqued in 2009 by Mistlberger et al. Fuller et al have responded to the critique with new information. Here we update our critique in the light of this new information. We also identify and correct factual and conceptual errors in the Fuller et al response. We conclude that the original results of Fuller et al remain inconclusive and fail to clarify the role of Bmal1 or the dorsomedial hypothalamus in the generation of food-entrainable rhythms in mice.",
    author = "Mistlberger, {Ralph E.} and Buijs, {Ruud M.} and Etienne Challet and Carolina Escobar and Landry, {Glenn J.} and Andries Kalsbeek and Paul Pevet and Shigenobu Shibata",
    year = "2009",
    month = "8",
    day = "10",
    doi = "10.1186/1740-3391-7-11",
    language = "English",
    volume = "7",
    journal = "Journal of Circadian Rhythms",
    issn = "1740-3391",
    publisher = "BioMed Central",

    }

    TY - JOUR

    T1 - Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice

    T2 - A reply to Fuller et al

    AU - Mistlberger, Ralph E.

    AU - Buijs, Ruud M.

    AU - Challet, Etienne

    AU - Escobar, Carolina

    AU - Landry, Glenn J.

    AU - Kalsbeek, Andries

    AU - Pevet, Paul

    AU - Shibata, Shigenobu

    PY - 2009/8/10

    Y1 - 2009/8/10

    N2 - Evidence that circadian food-anticipatory activity and temperature rhythms are absent in Bmal1 knockout mice and rescued by restoration of Bmal1 expression selectively in the dorsomedial hypothalamus was published in 2008 by Fuller et al and critiqued in 2009 by Mistlberger et al. Fuller et al have responded to the critique with new information. Here we update our critique in the light of this new information. We also identify and correct factual and conceptual errors in the Fuller et al response. We conclude that the original results of Fuller et al remain inconclusive and fail to clarify the role of Bmal1 or the dorsomedial hypothalamus in the generation of food-entrainable rhythms in mice.

    AB - Evidence that circadian food-anticipatory activity and temperature rhythms are absent in Bmal1 knockout mice and rescued by restoration of Bmal1 expression selectively in the dorsomedial hypothalamus was published in 2008 by Fuller et al and critiqued in 2009 by Mistlberger et al. Fuller et al have responded to the critique with new information. Here we update our critique in the light of this new information. We also identify and correct factual and conceptual errors in the Fuller et al response. We conclude that the original results of Fuller et al remain inconclusive and fail to clarify the role of Bmal1 or the dorsomedial hypothalamus in the generation of food-entrainable rhythms in mice.

    UR - http://www.scopus.com/inward/record.url?scp=69849094643&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=69849094643&partnerID=8YFLogxK

    U2 - 10.1186/1740-3391-7-11

    DO - 10.1186/1740-3391-7-11

    M3 - Article

    VL - 7

    JO - Journal of Circadian Rhythms

    JF - Journal of Circadian Rhythms

    SN - 1740-3391

    M1 - 11

    ER -