Formal Syntheses of Dictyodendrins B, C, and E by a Multi-Substituted Indole Synthesis

Akira Kabuki, Junichiro Yamaguchi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The dictyodendrins are a family of marine alkaloids, which possess a highly substituted pyrrolo[2,3-c]carbazole core. This core structure can be regarded as a multi-substituted indole and aniline moiety. To achieve a concise synthesis of dictyodendrins, we planned to capitalize on our previously developed multi-substituted indole synthesis. By using this method along with two C-H functionalizations, formal syntheses of dictyodendrins B, C, and E were achieved.

Original languageEnglish
Pages (from-to)4963-4970
Number of pages8
JournalSynthesis (Germany)
Volume54
Issue number22
DOIs
Publication statusPublished - 2022 Feb 12

Keywords

  • C-H functionalization
  • dictyodendrins
  • indole
  • ynamide
  • [4+2] cycloaddition

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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