From likes to dislikes: Conditioned taste aversion in the great pond snail (Lymnaea stagnalis)

Etsuro Ito, S. Kojima, K. Lukowiak, M. Sakakibara

Research output: Contribution to journalReview article

24 Citations (Scopus)

Abstract

The neural circuitry comprising the central pattern generator (CPG) that drives feeding behavior in the great pond snail (Lymnaea stagnalis (L., 1758)) has been worked out. Because the feeding behavior undergoes associative learning and long-term memory (LTM) formation, it provides an excellent opportunity to study the causal neuronal mechanisms of these two processes. In this review, we explore some of the possible causal neuronal mechanisms of associative learning of conditioned taste aversion (CTA) and its subsequent consolidation processes into LTM in L. stagnalis. In the CTA training procedure, a sucrose solution, which evokes a feeding response, is used as the conditioned stimulus (CS) and a potassium chloride solution, which causes a withdrawal response, is used as the unconditioned stimulus (US). The pairing of the CS-US alters both the feeding response of the snail and the function of a pair of higher order interneurons in the cerebral ganglia. Following the acquisition of CTA, the polysynaptic inhibitory synaptic input from the higher order interneurons onto the feeding CPG neurons is enhanced, resulting in suppression of the feeding response. These changes in synaptic efficacy are thought to constitute a "memory trace" for CTA in L. stagnalis.

Original languageEnglish
Pages (from-to)405-412
Number of pages8
JournalCanadian Journal of Zoology
Volume91
Issue number6
DOIs
Publication statusPublished - 2013 Jun
Externally publishedYes

Fingerprint

Lymnaea stagnalis
snail
snails
pond
interneurons
feeding behavior
learning
potassium chloride
sucrose
consolidation
neurons

Keywords

  • Conditioned taste aversion
  • Feeding
  • Long-term memory
  • Lymnaea stagnalis
  • Withdrawal

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Ecology, Evolution, Behavior and Systematics

Cite this

From likes to dislikes : Conditioned taste aversion in the great pond snail (Lymnaea stagnalis). / Ito, Etsuro; Kojima, S.; Lukowiak, K.; Sakakibara, M.

In: Canadian Journal of Zoology, Vol. 91, No. 6, 06.2013, p. 405-412.

Research output: Contribution to journalReview article

Ito, Etsuro ; Kojima, S. ; Lukowiak, K. ; Sakakibara, M. / From likes to dislikes : Conditioned taste aversion in the great pond snail (Lymnaea stagnalis). In: Canadian Journal of Zoology. 2013 ; Vol. 91, No. 6. pp. 405-412.
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