Abstract
A single molecule of F1-ATPase, a portion of ATP synthese, is by itself a rotary motor in which a central γ subunit rotates against a surrounding cylinder made of α3β3 subunits. Driven by three catalytic βs, each fueled with ATP, γ makes discrete 120°steps, occasionally stepping backward. The work done in each step is constant over a broad range of imposed load and is close to the free energy of hydrolysis of one ATP molecule.
Original language | English |
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Pages (from-to) | 1117-1124 |
Number of pages | 8 |
Journal | Cell |
Volume | 93 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1998 Jun 26 |
Externally published | Yes |
ASJC Scopus subject areas
- Cell Biology
- Molecular Biology