Abstract
A single molecule of F1-ATPase, a portion of ATP synthese, is by itself a rotary motor in which a central γ subunit rotates against a surrounding cylinder made of α3β3 subunits. Driven by three catalytic βs, each fueled with ATP, γ makes discrete 120°steps, occasionally stepping backward. The work done in each step is constant over a broad range of imposed load and is close to the free energy of hydrolysis of one ATP molecule.
| Original language | English |
|---|---|
| Pages (from-to) | 1117-1124 |
| Number of pages | 8 |
| Journal | Cell |
| Volume | 93 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1998 Jun 26 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cell Biology
- Molecular Biology
Cite this
F1-ATPase is a highly efficient molecular motor that rotates with discrete 120°steps. / Yasuda, Ryohei; Noji, Hiroyuki; Kinosita, Kazuhiko; Yoshida, Masasuke.
In: Cell, Vol. 93, No. 7, 26.06.1998, p. 1117-1124.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - F1-ATPase is a highly efficient molecular motor that rotates with discrete 120°steps
AU - Yasuda, Ryohei
AU - Noji, Hiroyuki
AU - Kinosita, Kazuhiko
AU - Yoshida, Masasuke
PY - 1998/6/26
Y1 - 1998/6/26
N2 - A single molecule of F1-ATPase, a portion of ATP synthese, is by itself a rotary motor in which a central γ subunit rotates against a surrounding cylinder made of α3β3 subunits. Driven by three catalytic βs, each fueled with ATP, γ makes discrete 120°steps, occasionally stepping backward. The work done in each step is constant over a broad range of imposed load and is close to the free energy of hydrolysis of one ATP molecule.
AB - A single molecule of F1-ATPase, a portion of ATP synthese, is by itself a rotary motor in which a central γ subunit rotates against a surrounding cylinder made of α3β3 subunits. Driven by three catalytic βs, each fueled with ATP, γ makes discrete 120°steps, occasionally stepping backward. The work done in each step is constant over a broad range of imposed load and is close to the free energy of hydrolysis of one ATP molecule.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032568695&partnerID=8YFLogxK
U2 - 10.1016/S0092-8674(00)81456-7
DO - 10.1016/S0092-8674(00)81456-7
M3 - Article
C2 - 9657145
AN - SCOPUS:0032568695
VL - 93
SP - 1117
EP - 1124
JO - Cell
JF - Cell
SN - 0092-8674
IS - 7
ER -