Functional brain mapping and electrophysiological monitoring during awake craniotomy for intraaxial brain lesions

Yoshihiro Muragaki, Takashi Maruyama, Hiroshi Iseki, Kintomo Takakura, Tomokatsu Hori

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Surgery for intracranial brain lesions located in the dominant hemisphere is associated with a high risk of postoperative speech disturbances. Detection of the functionally important cortical areas can be considered as a critical factor for avoidance of postoperative morbidity and for providing the optimal rate of resection for pathologies with narrow (gliomas) or absent (epileptic focus) microscopic borders with the normal cerebral tissue. Testing of the language function can be done preoperatively with the Wada test, functional MRI, and brain mapping with electrical stimulation after implantation of stereotactic electrodes or grid, and intraoperatively with cortical mapping and electrophysiological monitoring. Awake craniotomy provides the possibility for accurate localization of the eloquent brain areas. It permits us to define clearly the language area, the positive motor area, and the negative motor area, as well as the position of the white matter fibers connected with the speech and motor functions, and prevents both unexpected neurological complications and suboptimal lesion resection. Nevertheless, precise technique and clear differentiation between different types of possible neurophysiological responses are mandatory. Our technique for functional cortical mapping and electrophysiological monitoring during awake craniotomy for intraaxial brain lesions is presented herein.

Original languageEnglish
Pages (from-to)38-47
Number of pages10
JournalJapanese Journal of Neurosurgery
Volume17
Issue number1
Publication statusPublished - 2008 Jan
Externally publishedYes

Fingerprint

Brain Mapping
Craniotomy
Motor Cortex
Brain
Language
Glioma
Electric Stimulation
Electrodes
Magnetic Resonance Imaging
Pathology
Morbidity

Keywords

  • Brain tumor
  • Eloquent area
  • Removal

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Functional brain mapping and electrophysiological monitoring during awake craniotomy for intraaxial brain lesions. / Muragaki, Yoshihiro; Maruyama, Takashi; Iseki, Hiroshi; Takakura, Kintomo; Hori, Tomokatsu.

In: Japanese Journal of Neurosurgery, Vol. 17, No. 1, 01.2008, p. 38-47.

Research output: Contribution to journalArticle

Muragaki, Yoshihiro ; Maruyama, Takashi ; Iseki, Hiroshi ; Takakura, Kintomo ; Hori, Tomokatsu. / Functional brain mapping and electrophysiological monitoring during awake craniotomy for intraaxial brain lesions. In: Japanese Journal of Neurosurgery. 2008 ; Vol. 17, No. 1. pp. 38-47.
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